Cigarette smoking is at all-time lows globally, but the use of electronic cigarettes has
increased profoundly. Recent reports of electronic cigarette or vaping use-associated lung …

Cigarette smoking is the single most important risk factor for the development of
cardiovascular diseases (CVDs). However, the role of nicotine, the addictive component of …

Long-term nicotine intake is associated with an increased risk of myocardial damage and
dysfunction. However, it remains unclear whether targeting mitochondrial reactive oxygen …

Right ventricular (RV) fibrosis is a key feature of maladaptive RV hypertrophy and
dysfunction and is associated with poor outcomes in pulmonary hypertension (PH) …

The incidence of hypertension with diabetes mellitus (DM) as a co-morbid condition is on the
rise worldwide. In 2000, an estimated 972 million adults had hypertension, which is …

Background Electronic cigarette (e-cigarette) vapour is gaining popularity as an alternative
to tobacco smoking and can induce acute lung injury. However, the specific role of nicotine …

Use of electronic cigarettes is rapidly increasing among youth and young adults, but little is
known regarding the long-term cardiopulmonary health impacts of these nicotine-containing …

Introduction The impact of nicotine, the addictive component of both traditional cigarettes
and e-cigarettes, on many physiological processes remains poorly understood. To date …

Background and Purpose Cardiovascular disease affects up to half of the patients with
chronic obstructive pulmonary disease (COPD), exerting deleterious impact on health …

Despite claims of safety or harm reduction for electronic cigarettes (E-cig) use (also known
as vaping), emerging evidence indicates that E-cigs are not likely safe, or necessarily safer …