The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non …
H Quarsten, G Paulsen, BH Johansen… - International …, 1998 - academic.oup.com
Susceptibility and resistance to type 1 diabetes are associated with MHC class II alleles that
carry non-Asp and Asp at residue 57 of their beta chain respectively. The effect of Asp or non …
carry non-Asp and Asp at residue 57 of their beta chain respectively. The effect of Asp or non …
Both α and β chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with β chain residues being most influential
BH Johansen, T Jensen, CJ Thorpe, F Vartdal… - Immunogenetics, 1996 - Springer
We compared the peptide binding specificity of three HLA-DQ molecules; HLA-DQ (α1*
0501, β1* 0201), HLA-DQ (α1* 0201, β1* 0202), and HLA-DQ (α1* 0501, β1* 0301). The first …
0501, β1* 0201), HLA-DQ (α1* 0201, β1* 0202), and HLA-DQ (α1* 0501, β1* 0301). The first …
[PDF][PDF] Both αα and ββ chain polymorphisms determine the specificity of the disease-associated HLA-DQ2 molecules, with ββ chain residues being most influential
BH Johansen, T Jensen, CJ Thorpe, F Vartdal… - …, 1996 - academia.edu
Major histocompatibility complex (MHC) class II molecules are peptide receptors which
present fragments of degraded proteins to CD4+ T cells (Shimonkevitz et al. 1984; Germain …
present fragments of degraded proteins to CD4+ T cells (Shimonkevitz et al. 1984; Germain …