Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

Objective A decline in mitochondrial function and biogenesis as well as increased reactive
oxygen species (ROS) are important determinants of aging. With advancing age, there is a …

Alzheimer's disease (AD) is a neurodegenerative disorder linked to protein misfolding and
aggregation. AD is pathologically characterized by senile plaques formed by extracellular …

Synapse loss occurs normally during development and pathologically during
neurodegenerative disease. Long-term depression, a proposed physiological correlate of …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder, in which multiple risk
factors converge. Despite the complexity of the etiology of the disease, synaptic failure is the …

The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …

Alzheimer's disease (AD) is characterized by brain deposition of amyloid plaques and tau
neurofibrillary tangles along with steady cognitive decline. Although the mechanism by …

Alzheimer's disease (AD), characterized by cognitive decline, has emerged as a disease of
synaptic failure. The present study reveals an unanticipated role of erythropoietin-producing …

The defining features of Alzheimer's disease (AD) include alterations in protein aggregation,
immunity, lipid metabolism, synapses, and learning and memory. Of these, lipid …

Amyloid β (Aβ) oligomer-induced aberrant neurotransmitter release is proposed to be a
crucial early event leading to synapse dysfunction in Alzheimer's disease (AD). In the …