[HTML][HTML] Fentanyl and other opioid use disorders: treatment and research needs

ND Volkow, C Blanco - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
The opioid overdose epidemic, which has been markedly exacerbated by fentanyl,
highlights the urgency for psychiatrists to be well versed on the proper screening and …

Psychedelic targeting of metabotropic glutamate receptor 2 and its implications for the treatment of alcoholism

K Domanegg, WH Sommer, MW Meinhardt - Cells, 2023 - mdpi.com
Alcohol abuse is a leading risk factor for the public health burden worldwide. Approved
pharmacotherapies have demonstrated limited effectiveness over the last few decades in …

Mini-review: the neurobiology of treating substance use disorders with classical psychedelics

MM Urban, MR Stingl, MW Meinhardt - Frontiers in Neuroscience, 2023 - frontiersin.org
The potential of psychedelics to persistently treat substance use disorders is known since
the 1960s. However, the biological mechanisms responsible for their therapeutic effects …

Assessment of the acute subjective psychedelic experience: A review of patient-reported outcome measures in clinical research on classical psychedelics

OR Hovmand, ED Poulsen… - Journal of …, 2024 - journals.sagepub.com
Background: The classical psychedelics psilocybin, peyote, ayahuasca/N, N-
dimethyltryptamine, and lysergic acid diethylamide can temporarily produce altered states of …

Psychedelics, OCD and related disorders: A systematic review

M Graziosi, J Rohde, P Tiwari, J Siev… - Journal of Obsessive …, 2024 - Elsevier
This systematic review analyzes the current literature on the potential therapeutic use of
classic psychedelics (ie, psilocybin, lysergic acid diethylamide [LSD], N, N …

Psychedelics for treatment resistant depression: are they game changers?

M Kalfas, RH Taylor, D Tsapekos… - Expert opinion on …, 2023 - Taylor & Francis
Introduction A new era of treatment for adults with treatment-resistant depression (TRD),
which involves psychedelic substances, is dawning. Emerging evidence indicates that …

Potential use of psilocybin drugs in the treatment of depression

K Śladowska, P Kawalec, T Brzostek… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Depression is a common disabling psychiatric disorder, which–in extreme
cases–may lead to suicide if untreated or inadequately treated. Despite the availability of …

Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies

FF Hilal, J Jeanblanc, C Deschamps… - Journal of Neural …, 2024 - Springer
Alcohol use disorder (AUD) is a public health issue that affects millions of people worldwide
leading to physical, mental and socio-economic consequences. While current treatments for …

Health services for substance use disorders: challenges and future perspectives

JP Silva - BMC Health Services Research, 2023 - Springer
Research on the health services' response to substance use disorders and respective
comorbidities holds major relevance due to the increasing prevalence of these ailments. We …

Protocols and practices in psilocybin assisted psychotherapy for depression: a systematic review

N Chisamore, D Johnson, MJQ Chen, H Offman… - Journal of psychiatric …, 2024 - Elsevier
Background Psilocybin-assisted psychotherapy (PAP) is a promising treatment option for
depression, with randomized controlled trials (RCTs) providing preliminary support for its …