[HTML][HTML] Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: an evaluation of in vitro, in vivo methodologies and human studies

JWC Alffenaar, JEM de Steenwinkel… - Frontiers in …, 2022 - frontiersin.org
There has been an increased interest in pharmacokinetics and pharmacodynamics (PKPD)
of anti-tuberculosis drugs. A better understanding of the relationship between drug …

[HTML][HTML] Advances in computational frameworks in the fight against TB: The way forward

A Naidu, SS Nayak, S Lulu S… - Frontiers in …, 2023 - frontiersin.org
Around 1.6 million people lost their life to Tuberculosis in 2021 according to WHO estimates.
Although an intensive treatment plan exists against the causal agent, Mycobacterium …

[HTML][HTML] Discovery of potent antimycobacterial agents targeting lumazine synthase (RibH) of Mycobacterium tuberculosis

M Singh, A Dhanwal, A Verma, L Augustin, N Kumari… - Scientific Reports, 2024 - nature.com
Tuberculosis (TB) continues to be a global health crisis, necessitating urgent interventions to
address drug resistance and improve treatment efficacy. In this study, we validate lumazine …