Repetitive DNA motifs are abundant in the genomes of various species and have the
capacity to adopt non-canonical (ie, non-B) DNA structures. Several non-B DNA structures …

Accurate and complete replication of the genome in every cell division is a prerequisite of
genomic stability. Thus, both prokaryotic and eukaryotic replication forks are extremely …

DNA structure is a critical element in determining its function. The DNA molecule is capable
of adopting a variety of non-canonical structures, including three-stranded (ie triplex) …

DNA inverted repeats (IRs) are hotspots of genomic instability in both prokaryotes and
eukaryotes. This feature is commonly attributed to their ability to fold into hairpin-or cruciform …

Abstract Background The use of RNAseq to resolve the transcriptional organization of an
organism was established in recent years and also showed the complexity and dynamics of …

The ability of double-stranded DNA to form a triple-helical structure by hydrogen bonding
with a third strand is well established, but the biological functions of these structures remain …

Specific gene expression involves the binding of natural ligands to the DNA base pairs.
Among the compounds rationally designed for artificial regulation of gene expression …

Nucleic acids (DNA and RNA) dynamically fold and unfold to exert their functions in cells.
These folding and unfolding behaviours are also the basis for various technical applications …

Interstrand DNA crosslinks (ICLs) are formed by natural products of metabolism and by
chemotherapeutic reagents. Work in E. coli identified a two cycle repair scheme involving …

DNA forms not only the canonical duplex structure but also non-canonical structures. Most
potential sequences that induce the formation of non-canonical structures are present in …