Perfect short inverted repeats (IRs) are known to be enriched in a variety of bacterial and
eukaryotic genomes. Currently, it is unclear whether perfect IRs are conserved over …

Enrichment of four tandem repeats of guanine (G) rich and cytosine (C) rich sequences in
functionally important regions of human genome forebodes the biological implications of …

Inverted repeats are unstable motifs in a genome, having a causal relation to fragment
rearrangements and recombination events. We have investigated long inverted repeats …

Although a gene's location can greatly influence its expression, genome sequencing has
shown that orthologous genes may exist in very different environments in the genomes of …

Instabilities that are intrinsic to natural repetitive DNA sequences produce high frequencies
of length changesin vivo. Triplet repeats cloned in plasmids inEscherichia coliundergo …

Triplex DNA is implicated in a wide range of biological activities, including regulation of
gene expression and genomic instability leading to cancer. The tumor suppressor p53 is a …

The promoter region of the chicken α2 (I) collagen gene contains a pyrimidine-rich element
that is well conserved in different mammalian species. This sequence can also form an …

DNA sequences capable of forming triplexes are prevalent in the human genome and have
been found to be intrinsically mutagenic. Consequently, a balance between DNA repair and …

Motivation: Current methods for identification of potential triplex-forming sequences in
genomes and similar sequence sets rely primarily on detecting homopurine and …

Several non-Watson Crick DNA structures have been discovered to date, which may be
incorporated into future plasmid constructs for gene therapy and DNA vaccine products. In …