Structural polymorphism of DNA is a widely accepted property. A simple addition to this
perception has been our recent finding, where a single nucleotide polymorphism (SNP) site …

The formation of triple‐helical DNA is implicated in the regulation of gene expression. The
triplexes are, however, unstable under physiological conditions so that effective stabilizers …

Local structural transitions from the common B-DNA conformation into other DNA forms can
be functionally important. This chapter describes the structures of DNA forms called …

Motivation: Comparative genomics provides a powerful way to investigate regularities and
differences observed at DNA level across species. Here we study the number and location …

DNA sequences capable of forming triplexes induce DNA double-strand breaks that have
attracted attention in genome editing technologies (eg, CRISPR/Cas9 system, TALEN, and …

Multiple types of non-canonical nucleic acid structures play essential roles in DNA
recombination and replication, transcription, and genomic instability and have been …

Nucleic acids are polymorphic macromolecules that can adopt a variety of single-, double-
and multi-stranded conformations, which in turn may provide important signals for regulating …

The canonical double-helix form of DNA is thought to predominate both in dilute solution
and in living cells. Sequence-dependent fluctuations in local DNA shape occur within the …

Abstract Effects of d (CAG) n· d (CTG) n repeats on expression of a reporter gene in human
cell culture were studied using transient transfection, RNase protection and coupled …

We previously used a pattern recognition program for nucleic acids to detect sequences with
the potential to form intrastrand triplexes. Potential intrastrand triplex (PIT) element families …