In 1984, the first venom phospholipase A2 (PLA2) with a lysine substituting for the highly
conserved aspartate 49 was discovered, in the North American crotalid snake Agkistrodon p …

Snake venoms often contain toxins that cause a rapid necrosis of skeletal muscle fibers,
referred to as myotoxins. The most common among them are phospholipases A2 (PLA2s) …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Snake venom phospholipases A2 (PLA2) show a remarkable functional diversity. Among
their toxic activities, some display the ability to cause rapid necrosis of skeletal muscle fibers …

Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …

The isolation and biochemical/enzymatic characterization of an l-amino acid oxidase, Balt-
LAAO-I, from Bothrops alternatus snake venom, is described. Balt-LAAO-I is an acidic …

Venoms from eight Bothrops spp. were fractionated by ion-exchange chromatography on
CM-Sepharose at pH 8.0 for the purification of myotoxins. Chromatographic profiles showed …

Envenomation via snakebites is an important public health problem in many tropical and
subtropical countries that, in addition to mortality, can result in permanent sequelae as a …

The crude aqueous extract from the leaves of Casearia sylvestris, a plant found in Brazilian
open pastures, was assayed for its ability to inhibit phospholipase A2 (PLA2) activity and …