Oral squamous cell carcinoma (OSCC) is a malignant disease in the world which has a
profound effect on human health and life quality. According to tumor stage and pathological …

Simple Summary Head and Neck Squamous Cell Carcinoma (HNSCC) is a major threat to
public health around the world. Its occurrence is linked to genetic events and environmental …

Lipid metabolism reprogramming is one of the most prominent metabolic anomalies in
cancer, wherein cancer cells undergo dysregulation of lipid metabolism to acquire adequate …

Fanconi anemia (FA) is a rare hereditary disease resulting from an inactivating mutation in
the FA/BRCA pathway, critical for the effective repair of DNA interstrand crosslinks (ICLs) …

Precancerous cells in the oral cavity may appear as oral potentially malignant disorders, but
they may also present as dysplasia without visual manifestation in tumor-adjacent tissue. As …

Abstract Cytokeratin 10 (CK10) is a type I acidic low molecular weight cytokeratin which is
mainly expressed in keratinizing squamous epithelium of the skin. Variable levels of CK10 …

Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is
essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining …

Although numerous putative oncogenes have been associated with the etiology of head and
neck squamous cell carcinoma (HNSCC), the mechanisms by which these oncogenes and …

Background There are many studies regarding the use of systemic immune-inflammation
index (SII) to help predict oral squamous cell carcinoma (OSCC) prognosis, but findings …

About two-thirds of the patients with head and neck squamous cell carcinoma present with
locoregionally advanced disease (LA-HNSCC). These patients have a 5-year overall …