Somatosensory afferents are traditionally classified by soma size, myelination, and their
response specificity to external and internal stimuli. Here, we propose the functional …

Importance Chronic back pain (CBP) is a leading cause of disability, and treatment is often
ineffective. Approximately 85% of cases are primary CBP, for which peripheral etiology …

The COVID-19 pandemic is associated with an increased prevalence of mental health
problems and addictive behaviors. There is a growing theoretical and empirical evidence …

In recent years, the societal and personal impacts of pain, and the fact that we still lack an
effective method of treatment, has motivated researchers from diverse disciplines to try to …

Contemporary conceptualizations of pain emphasize its protective function. The meaning
assigned to pain drives cognitive, emotional, and behavioral responses. When pain is …

Importance In primary chronic back pain (CBP), the belief that pain indicates tissue damage
is both inaccurate and unhelpful. Reattributing pain to mind or brain processes may support …

BACKGROUND: Generic self-report measures do not reflect the complexity of a person's
pain-related behavior. Since variations in a person's fear of movement and avoidance …

This special issue celebrates the 100th anniversary of the Little Albert study, published in
February 1920, which marked the birth of human fear conditioning research. The collection …

Anxiety and depression are frequently observed in patients suffering from trigeminal
neuralgia (TN), but neural circuits and mechanisms underlying this association are poorly …

The formation and persistence of negative pain-related expectations by classical
conditioning remain incompletely understood. We elucidated behavioural and neural …