[HTML][HTML] miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …

[HTML][HTML] microRNAs (miRNAs) in glioblastoma multiforme (GBM)—recent literature review

M Makowska, B Smolarz, H Romanowicz - International Journal of …, 2023 - mdpi.com
Glioblastoma multiforme (GBM) is the most common, malignant, poorly promising primary
brain tumor. GBM is characterized by an infiltrating growth nature, abundant vascularization …

A hybrid cancer prediction based on multi-omics data and reinforcement learning state action reward state action (SARSA)

MA Mohammed, A Lakhan, KH Abdulkareem… - Computers in Biology …, 2023 - Elsevier
These days, the ratio of cancer diseases among patients has been growing day by day.
Recently, many cancer cases have been reported in different clinical hospitals. Many …

miR-136-5p: A key player in human cancers with diagnostic, prognostic and therapeutic implications

CY Hsu, OQB Allela, SAH Mahdi, OP Doshi… - … -Research and Practice, 2023 - Elsevier
MiRNAs have emerged as crucial modulators of the expression of their target genes,
attracting significant attention due to their engagement in various cellular processes, like …

Federated auto-encoder and XGBoost schemes for multi-omics cancer detection in distributed fog computing paradigm

MA Mohammed, A Lakhan, KH Abdulkareem… - Chemometrics and …, 2023 - Elsevier
The digital healthcare paradigm has significantly improved based on distributed fog and
cloud networks for cancer detection with multiple classes in recent years. The paradigm …

[HTML][HTML] FOXO1, a tiny protein with intricate interactions: Promising therapeutic candidate in lung cancer

M Ebrahimnezhad, M Natami, GH Bakhtiari… - Biomedicine & …, 2023 - Elsevier
Nowadays, lung cancer is the most common cause of cancer-related deaths in both men
and women globally. Despite the development of extremely efficient targeted agents, lung …

[HTML][HTML] Crosstalk between miRNAs and DNA Methylation in Cancer

M Saviana, P Le, L Micalo, D Del Valle-Morales… - Genes, 2023 - mdpi.com
miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

Oxidative stress and redox-dependent signaling in prostate cancer

EV Kalinina, LA Gavriliuk, VS Pokrovsky - Biochemistry (Moscow), 2022 - Springer
Tumor emergence and progression is complicated by the dual role of reactive oxygen
species (ROS). Low concentrations of ROS are essential for many intracellular metabolic …

[HTML][HTML] The feedback loop of METTL14 and USP38 regulates cell migration, invasion and EMT as well as metastasis in bladder cancer

J Huang, W Zhou, C Hao, Q He, X Tu - PLoS Genetics, 2022 - journals.plos.org
Background Bladder cancer (BCa) is one of the most prevalent malignancies globally.
Previous study has reported the inhibitory effect of methyltransferase-like 14 (METTL14) on …

Pan-cancer genetic analysis of disulfidptosis-related gene set

H Liu, T Tang - Cancer Genetics, 2023 - Elsevier
Background A recent study has identified a novel programmed cell death pathway, termed
disulfidptosis, which is based on disulfide proteins. This discovery provides new insight into …