Runx2 (runt-related transcription factor 2)-mediated microcalcification is a novel pathological characteristic and potential mediator of abdominal aortic aneurysm
Z Li, Z Zhao, Z Cai, Y Sun, L Li, F Yao… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Abdominal aortic aneurysms (AAAs) are highly lethal diseases without effective
clinical predictors and therapeutic targets. Vascular microcalcification, as detected by …
clinical predictors and therapeutic targets. Vascular microcalcification, as detected by …
Carbon monoxide releasing molecule-2 attenuates angiotensin II-induced IL-6/Jak2/Stat3-associated inflammation by inhibiting NADPH oxidase-and mitochondria …
CY Hsu, TTT Vo, CW Lee, YL Chen, WN Lin… - Biochemical …, 2022 - Elsevier
Abdominal aortic aneurysm (AAA) is a common inflammatory vascular disease. Angiotensin
II (Ang II) involves in AAA progression by promoting the proliferation and migration of …
II (Ang II) involves in AAA progression by promoting the proliferation and migration of …
Targeted drug delivery of magnetic microbubble for abdominal aortic aneurysm: an in silico study
A Shamloo, S Ebrahimi, G Ghorbani… - … and Modeling in …, 2022 - Springer
Targeted drug delivery (TDD) to abdominal aortic aneurysm (AAA) using a controlled and
efficient approach has recently been a significant challenge. In this study, by using magnetic …
efficient approach has recently been a significant challenge. In this study, by using magnetic …
Aorta regulatory T cells with a tissue‐specific phenotype and function promote tissue repair through Tff1 in abdominal aortic aneurysms
J Li, N Xia, D Li, S Wen, S Qian, Y Lu, M Gu… - Advanced …, 2022 - Wiley Online Library
In addition to maintaining immune tolerance, Foxp3+ regulatory T cells (Tregs) perform
specialized functions in tissue homeostasis and remodeling. However, whether Tregs in …
specialized functions in tissue homeostasis and remodeling. However, whether Tregs in …
Proteomics applications in biomarker discovery and pathogenesis for abdominal aortic aneurysm
J Wu, W Wang, Z Chen, F Xu… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Abdominal aortic aneurysm (AAA) is a common, complex, and life-threatening
disease. Currently, the pathogenesis of AAA is not well understood. No biomarkers or …
disease. Currently, the pathogenesis of AAA is not well understood. No biomarkers or …
[HTML][HTML] Genetic predisposition to diabetes and abdominal aortic aneurysm: a two stage Mendelian randomisation study
Objective Observational studies demonstrate an inverse association between type II
diabetes and abdominal aortic aneurysm (AAA) for reasons that are unclear. The aim of this …
diabetes and abdominal aortic aneurysm (AAA) for reasons that are unclear. The aim of this …
Circular RNA expression: Its potential regulation and function in abdominal aortic aneurysms
Abdominal aortic aneurysms (AAAs) have posed a great threat to human life, and the
necessity of its monitoring and treatment is decided by symptomatology and/or the aneurysm …
necessity of its monitoring and treatment is decided by symptomatology and/or the aneurysm …
Pharmacotherapy in clinical trials for abdominal aortic aneurysms: A systematic review and meta-analysis
Z Su, J Guo, Y Gu - Clinical and Applied Thrombosis …, 2022 - journals.sagepub.com
Objective There is no medical treatment proven to limit abdominal aortic aneurysm (AAA)
progression. This systematic review aimed to summarise available trial evidence on the …
progression. This systematic review aimed to summarise available trial evidence on the …
High NOR-1 (neuron-derived orphan receptor 1) expression strengthens the vascular wall response to angiotensin II leading to aneurysm formation in mice
L Cañes, I Martí-Pàmies, C Ballester-Servera… - …, 2021 - Am Heart Assoc
No drug therapy has shown to limit abdominal aortic aneurysm (AAA) growth or rupture, and
the understanding of the disease biology is incomplete; whereby, one challenge of vascular …
the understanding of the disease biology is incomplete; whereby, one challenge of vascular …
Gut microbiota influence the development of abdominal aortic aneurysm by suppressing macrophage accumulation in mice
R Shinohara, H Nakashima, T Emoto, T Yamashita… - …, 2022 - Am Heart Assoc
Background: Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease
characterized by dilated abdominal aorta. Immune cells have been shown to contribute to …
characterized by dilated abdominal aorta. Immune cells have been shown to contribute to …