Virus‐Inspired Mimics Based on Dendritic Lipopeptides for Efficient Tumor‐Specific Infection and Systemic Drug Delivery

Z Zhang, X Zhang, X Xu, Y Li, Y Li… - Advanced Functional …, 2015 - Wiley Online Library
Herein, multifunctional mimics of viral architectures and infections self‐assembled from tailor‐
made dendritic lipopeptides for programmed targeted drug delivery are reported. These viral …

Stiffness of HIV‐1 Mimicking Polymer Nanoparticles Modulates Ganglioside‐Mediated Cellular Uptake and Trafficking

B Eshaghi, N Alsharif, X An, H Akiyama… - Advanced …, 2020 - Wiley Online Library
The monosialodihexosylganglioside, GM3, and its binding to CD169 (Siglec‐1) have been
indicated as key factors in the glycoprotein‐independent sequestration of the human …

Biomimetic virus-like mesoporous silica nanoparticles improved cellular internalization for co-delivery of antigen and agonist to enhance Tumor immunotherapy

Y Gao, Y Zhang, H Xia, Y Ren, H Zhang, S Huang… - Drug …, 2023 - Taylor & Francis
Nanocarrier antigen-drug delivery system interacts specifically with immune cells and
provides intelligent delivery modes to improve antigen delivery efficiency and facilitate …

Understanding the contribution of surface roughness and hydrophobic modification of silica nanoparticles to enhanced therapeutic protein delivery

Y Niu, M Yu, A Meka, Y Liu, J Zhang… - Journal of Materials …, 2016 - pubs.rsc.org
Intracellular protein delivery holds great promise for cancer therapy. In this work, the
individual and combined contribution of the surface roughness and hydrophobic …

In situ Stöber templating: facile synthesis of hollow mesoporous carbon spheres from silica–polymer composites for ultra-high level in-cavity adsorption

O Noonan, H Zhang, H Song, C Xu… - Journal of Materials …, 2016 - pubs.rsc.org
Hollow structuring of carbon materials with mesoporous walls has been shown to enhance
performance in a range of adsorption-based applications. However, utilization of the in …

Virus-inspired nanosystems for drug delivery

Z Liao, L Tu, X Li, XJ Liang, S Huo - Nanoscale, 2021 - pubs.rsc.org
With over millions of years of evolution, viruses can infect cells efficiently by utilizing their
unique structures. Similarly, the drug delivery process is designed to imitate the viral …

Biomimetic bacterial and viral-based nanovesicles for drug delivery, theranostics, and vaccine applications

YS Loo, RJC Bose, JR McCarthy, IDM Azmi… - Drug Discovery …, 2021 - Elsevier
Highlights•Biomimetic enable the safe integration of naturally-occurring bacteria and virus
particles.•Bioinspired materials comprise the development of novel nanomedicines and …

Silica-based nanoparticles for therapeutic protein delivery

M Yu, Z Gu, T Ottewell, C Yu - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Nowadays, protein therapeutics receive unprecedented recognition for their great potential
in the treatment of a variety of diseases. The efficacy of native therapeutic proteins is limited …

Functionalized materials for multistage platforms in the oral delivery of biopharmaceuticals

F Araujo, J das Neves, JP Martins, PL Granja… - Progress in Materials …, 2017 - Elsevier
Recent developments in materials science and specific surface functionalization of materials
are providing new tools for the rational design of precisely engineered drug delivery …

Parishin A-loaded mesoporous silica nanoparticles modulate macrophage polarization to attenuate tendinopathy

L Zhu, Y Wang, S Jin, Y Niu, M Yu, Z Li… - NPJ Regenerative …, 2023 - nature.com
Macrophages are involved mainly in the balance between inflammation and tenogenesis
during the healing process of tendinopathy. However, etiological therapeutic strategies to …