Combined anti-angiogenic and anti-inflammatory nanoformulation for effective treatment of ocular vascular diseases

J Sun, H Nie, P Pan, Q Jiang, C Liu… - International Journal …, 2023 - Taylor & Francis
Background Ocular vascular diseases are the major causes of visual impairment, which are
characterized by retinal vascular dysfunction and robust inflammatory responses. Traditional …

Improving the utilization rate of foliar nitrogen fertilizers by surface roughness engineering of silica spheres

W Li, R Fan, H Zhou, Y Zhu, X Zheng, M Tang… - Environmental …, 2020 - pubs.rsc.org
Compared with root nitrogen fertilizers, foliar nitrogen fertilizers (FNFs) have been widely
used for crop growth due to their high fertilizer efficiency and high utilization rate, especially …

Tumor heterogeneity and nanoparticle-mediated tumor targeting: the importance of delivery system personalization

KL Swetha, A Roy - Drug delivery and translational research, 2018 - Springer
After the discovery of the enhanced permeability and retention effect in 1986, it was
envisioned that nanoparticle-mediated tumor-targeted delivery of chemotherapeutics would …

Petaloid Metal–Organic Frameworks for Resiquimod Delivery To Potentiate Antitumor Immunity

C Zhang, Z Deng, X Sun, K Yuan, J Wang… - … Applied Materials & …, 2024 - ACS Publications
The morphological features of materials significantly influence their interactions with cells,
consequently affecting the cellular uptake of these materials. In this study, we examine the …

Surface modification and local orientations of surface molecules in nanotherapeutics

ML Amin, JY Joo, DK Yi, SSA An - Journal of Controlled Release, 2015 - Elsevier
Nanotechnology has emerged as a powerful tool for various therapeutic applications,
solving many difficulties in both diagnosis and treatment. However, many obstacles in …

Synthesis of photo-excited Chlorin e6 conjugated silica nanoparticles for enhanced anti-bacterial efficiency to overcome methicillin-resistant Staphylococcus aureus

J Lin, J Li, A Gopal, T Munshi, Y Chu, J Wang… - Chemical …, 2019 - pubs.rsc.org
Multidrug resistant bacterial infection remains a significant public concern. In this report,
photosensitizer Chlorin e6 doped silica was synthesized. This hybrid structure exhibits …

Controlling the Surface Morphology of Two-Dimensional Nano-Materials upon Molecule-Mediated Crystal Growth

T Yamaguchi, HJ Kim, HJ Park, T Kim, Z Khalid… - Nanomaterials, 2023 - mdpi.com
The surface morphology of Mg-Al-layered double hydroxide (LDH) was successfully
controlled by reconstruction during systematic phase transformation from calcined LDH …

Silica nanoparticles with virus-mimetic spikes enable efficient siRNA delivery in vitro and in vivo

J Fu, W Han, X Zhang, Y Sun, R Bhadane, B Wei, L Li… - Research, 2022 - spj.science.org
Oligonucleotide-based therapy has experienced remarkable development in the past 2
decades, but its broad applications are severely hampered by delivery vectors. Widely used …

Virus‐inspired hollow mesoporous gadolinium‐bismuth nanotheranostics for magnetic resonance imaging‐guided synergistic photodynamic‐radiotherapy

Z Liu, P Wang, F Xie, J Chen, M Cai, Y Li… - Advanced …, 2022 - Wiley Online Library
The anti‐tumor efficacy of single photodynamic therapy (PDT) and radiotherapy (RT) has
been greatly affected by inadequate tumor uptake of photo/radiation sensitizers, limited laser …

Synthetic biology and tissue engineering: toward fabrication of complex and smart cellular constructs

T Hoffman, P Antovski, P Tebon, C Xu… - Advanced Functional …, 2020 - Wiley Online Library
Tissue engineering approaches, with the goals of replacing or recovering damaged or
diseased tissues, or of reconstituting tissues in vitro for disease modeling and drug …