Hypothesis Colloids with rough topography demonstrate more complex interactions and
tremendous potential in industrial applications. However, relevant studies suffer from a …

Biogenic and biomimetic therapeutics are a relatively new class of systems that are of
physiological origin and/or take advantage of natural pathways or aim at mimicking these to …

Polymer–inorganic hybrid nanomaterials have attracted much attention for the multimodal
cancer therapy, while it is still desirable to explore hybrids with superior morphologies for …

Cancer radiotherapy is one of the most effective regimens of cancer treatments, but cancer
cell radioresistance remains a concern. Radiosensitizers can selectively improve the …

The choice of nanocarriers is crucial to fabricate ideal therapeutic nanoplatform in the
treatment of cancer. Considering the advantages brought by the two-dimensional (2D) …

Nanosized oncolytic viral light particles (L-particles), separated from progeny virions, are
composed of envelopes and several tegument proteins of viruses, free of nucleocapsids …

Silencing genes using small interfering (si) RNA is a promising strategy for treating cancer.
However, the curative effect of siRNA is severely constrained by low serum stability and cell …

Effective delivery of imaging agents or therapeutics to the brain has remained elusive due to
the poor blood-brain barrier (BBB) permeability, resulting in the apparent risks of inefficient …

The low delivery efficiency of nanoparticles to solid tumors greatly reduces the therapeutic
efficacy and safety which is closely related to low permeability and poor distribution at tumor …

Intricately structured mesoporous organosilica nanoparticles (IMONs) are being increasingly
studied from their synthesis strategies to their use in biomedical applications, because of …