Overall, there is dearth of reliable data on key epidemiological factors, including the
prevalence rates, and on objective and reliable indices of the risk/safety profiles. Rigorous …

As the world's first oral nuclear export inhibitor, selinexor is increasingly being used in
clinical applications for malignant tumors. However, there is no extensive exploration on …

Background While FDA-approved treatments exist for opioid use disorder, none are
available for stimulant use disorder. Kratom (Mitragyna speciosa), an unregulated plant …

Loperamide is an over‐the‐counter peripheral mu‐opioid agonist commonly used to
manage diarrhoea. When taken in an excessive dose, loperamide's penetration of the …

The opioid epidemic continues to claim thousands of lives annually, with provisional data
reporting 80,000 opioid-attributed deaths in 2022. 1 Emerging data on the cardiotoxic effects …

Dr Font and colleagues provide persuasive observational evidence that the over-the-counter
antidiarrheal drug loperamide is associated with cardiac conduction and rhythm …

The information component (IC) is an indicator for disproportionate Bayesian reporting that
compares observed and expected values for a studied drug (ie, loperamide) vs the full …

The article discusses the Center for Food Safety and Applied Nutrition Adverse Event
Reporting System (CAERS) as a national database for food, dietary supplements, and …