Literature data has shown that acute administration of magnesium reduces immobility time
in the mouse forced swimming test (FST), which suggests potential antidepressant activity in …

The present study examined the hyponociceptive effect of swimming exercise in a chemical
behavioral model of nociception and the mechanisms involved in this effect. Male mice were …

The present study examined the antinociceptive effect of the ethanolic extract from Melissa
officinalis L. and of the rosmarinic acid in chemical behavioral models of nociception and …

Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is a phenolic compound present in several
plants with claimed beneficial effects in prevention and treatment of disorders linked to …

Increasing evidence shows that inflammation may contribute to the pathophysiology of
depression. Apigenin, one type of natural flavone, has a number of biological actions …

The forced swim test (FST) is a preclinical test to the screening of antidepressants based on
rats or mice behaviours, which is also sensitive to stimulants of motor activity. This work …

Experiments were designed to address whether the pentacyclic triterpene tormentic acid
isolated from the stem bark of the plant Vochysia divergens exerts oral anti-allodynic …

The present study examined the antinociceptive effects of agmatine in chemical behavioural
models of pain. Agmatine (1–30 mg/kg), given by ip route, 30 min earlier, produced dose …

Perillaldehyde (PAH), a major component of essential oil of Perilla Frutescens, has
antidepressant-like effects and anti-inflammatory effects. The present study was designed to …

The present study examined the antinociceptive effects of the ethanolic extract (EE) and of
the triterpene 3β, 6β, 16β-trihidroxilup-20 (29)-ene obtained from the flowers of Combretum …