Neuropeptide Y (NPY) is thought to be implicated in depressive disorders. The mouse
forced swim test (FST) is an animal model widely used as a predictor of the efficacy of …

Background: Human's existence has become more stressful these days, most likely for the
sake of improving one's lifestyle and fulfilling one's aspirations and needs. Depression is the …

Abstract Jiao-Tai-Wan (JTW), has been usually used for insomnia in traditional Chinese
medicine (TCM). The previous study shown that JTW was benefit for depression-like …

Our study sought to evaluate the anxiolytic and antidepressant activities of oleanolic acid as
well as the neural mechanisms involved. Animal models such as barbiturate sleep …

Abstract β-amyloid (Aβ) accumulation is a major neuropathological characteristic of
Alzheimer's disease (AD) and serves as an inflammatory stimulus for microglial cells …

In the present study, the potential antidepressant properties of asiaticoside were
investigated in male mice in three tests—splash test in the unpredictable chronic mild stress …

Purpose The efficacy of current antidepressant drugs has been compromised by adverse
effects, low remission and delay onset of action necessitating the search for alternative …

In this study, the antidepressant-like effect caused by diphenyl diselenide on rat forced
swimming test (FST) was investigated. The involvement of the monoaminergic system in the …

Alzheimer's disease (AD) is characterized by progressive cognitive impairments as well as
non-cognitive symptoms such as depressed mood. Physical exercise has been proposed as …