Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation

SY Lee, EK Jeong, MK Ju, HM Jeon, MY Kim, CH Kim… - Molecular cancer, 2017 - Springer
Radiation therapy is one of the major tools of cancer treatment, and is widely used for a
variety of malignant tumours. Radiotherapy causes DNA damage directly by ionization or …

[HTML][HTML] Radiation, inflammation, and immune responses in cancer

G Multhoff, J Radons - Frontiers in oncology, 2012 - frontiersin.org
Chronic inflammation has emerged as one of the hallmarks of cancer. Inflammation also
plays a pivotal role in modulating radiation responsiveness of tumors. As discussed in this …

Bringing the heavy: carbon ion therapy in the radiobiological and clinical context

CD Schlaff, A Krauze, A Belard, JJ O'Connell… - Radiation …, 2014 - Springer
Radiotherapy for the treatment of cancer is undergoing an evolution, shifting to the use of
heavier ion species. For a plethora of malignancies, current radiotherapy using photons or …

[HTML][HTML] Cancer stem cells and signaling pathways in radioresistance

L Chang, P Graham, J Hao, J Ni, J Deng, J Bucci… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Radiation therapy (RT) is one of the most important strategies in cancer treatment.
Radioresistance (the failure to RT) results in locoregional recurrence and metastasis …

In vivo study of breast carcinoma radiosensitization by targeting eIF4E

H Yang, LW Li, M Shi, JH Wang, F Xiao, B Zhou… - Biochemical and …, 2012 - Elsevier
BACKGROUND: Eukaryotic initiation factor eIF4E, an important regulator of translation,
plays a crucial role in the malignant transformation, progression and radioresistance of …

Myricanol Induces Apoptotic Cell Death and Anti-Tumor Activity in Non-Small Cell Lung Carcinoma in Vivo

G Dai, Y Tong, X Chen, Z Ren, X Ying, F Yang… - International Journal of …, 2015 - mdpi.com
This study explored the inhibiting effect and mechanism of myricanol on lung
adenocarcinoma A549 xenografts in nude mice. Forty nude mice with subcutaneous A549 …

PDGFRβ and HIF-1α inhibition with imatinib and radioimmunotherapy of experimental prostate cancer

Y Kimura, K Inoue, M Abe, J Nearman… - Cancer biology & …, 2007 - Taylor & Francis
The clinical application of radioimmunotherapy (RIT) as a single modality in the treatment of
prostate cancer is held back because of poor tumor responses to RIT and unacceptable …

Spinal cord stimulation versus reoperation for failed back surgery syndrome: a cost effectiveness and cost utility analysis based on a randomized, controlled trial

HA Wilkinson - Neurosurgery, 2008 - journals.lww.com
To the Editor: We read with interest the article by Donovan and Person (1). This article
described the use of vacuum-assisted closure therapy for a large scalp defect resulting from …

Contribution of neuropilin-1 in radiation-survived subclones of NSCLC cell line H1299

K Tsutsumi, A Chiba, Y Tadaki, S Minaki… - Current Issues in …, 2021 - mdpi.com
Non-small cell lung cancer (NSCLC) is an aggressive lung cancer accounting for
approximately 85% of all lung cancer patients. For the patients with Stages IIIA, IIIB, and IIIC …

肿瘤放射治疗增敏剂研究新进展

李卫红, 王浩, 周晓靓, 周则卫 - 国际放射医学核医学杂志, 2013 - ijrmnm.com
目前除传统的亲电子放射增敏剂硝基咪唑类, 硝基苯等之外, 还发现了部分化疗药物也具有肿瘤
放射治疗增敏效果. 分子靶向药物的研究方兴未艾, 分别作用于组蛋白去乙酰化酶 …