[HTML][HTML] De novo metastatic prostate cancer: Are we moving toward a personalized treatment?

C Piombino, M Oltrecolli, E Tonni, M Pirola, R Matranga… - Cancers, 2023 - mdpi.com
Simple Summary De novo metastatic hormone-sensitive prostate cancer usually has a
dismal prognosis, which has slightly improved in recent years thanks to the introduction of …

[HTML][HTML] Optimal Dosing and Patient Selection for Electrochemotherapy in Solid Abdominal Organ and Bone Tumors

CH Martin, RCG Martin - Bioengineering, 2023 - mdpi.com
The primary aim of this study was to analyze studies that use electrochemotherapy (ECT) in
“deep-seated” tumors in solid organs (liver, kidney, bone metastasis, pancreas, and …

Regenerating murine CD8+ lung tissue resident memory T cells after targeted radiation exposure

M Hassert, LL Pewe, R He, M Heidarian… - Journal of Experimental …, 2024 - rupress.org
Radiation exposure occurs during medical procedures, nuclear accidents, or spaceflight,
making effective medical countermeasures a public health priority. Naïve T cells are highly …

Light stimulation of mitochondria reduces blood glucose levels

MB Powner, G Jeffery - Journal of Biophotonics, 2024 - Wiley Online Library
Mitochondria regulate metabolism, but solar light influences its rate. Photobiomodulation
(PBM) with red light (670 nm) increases mitochondrial membrane potentials and adenosine …

[HTML][HTML] BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors

AP Conley, CL Roland, A Bessudo, BR Gastman… - Cancer gene …, 2024 - nature.com
AdAPT-001 is an oncolytic adenovirus (OAV) with a transforming growth factor beta (TGF-ß)
trap, which neutralizes the immunosuppressive and profibrotic cytokine, TGF-ß. The aim or …

Radiotherapy with or without immunotherapy in metastatic melanoma: efficacy and tolerability

E Backlund, V Grozman, S Egyhazi Brage… - Acta …, 2023 - Taylor & Francis
Introduction Radiotherapy (RT) is primarily considered as a palliative treatment in patients
with metastatic melanoma. However, observations suggest that when RT is combined with …

Reappraisal of the role of radiation therapy in lymphoma treatment

L Specht - Hematological Oncology, 2023 - Wiley Online Library
Radiation therapy (RT) for lymphomas has improved dramatically with modern imaging and
treatment techniques, encompassing only the necessary volume with minimal doses to …

[HTML][HTML] The role of immunotherapy sensitizers and novel immunotherapy modalities in the treatment of cancer

G Sacchi de Camargo Correia, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
The importance of the immune system in the response against cancer has always been a
subject of intense investigation. The advent of immune checkpoint inhibitors has transformed …

[HTML][HTML] Non-cellular immunotherapies in pediatric central nervous system tumors

S Rumler - Frontiers in Immunology, 2023 - frontiersin.org
Central nervous system (CNS) tumors are the second most common type of cancer and the
most common cause of cancer death in pediatric patients. New therapies are desperately …

An overview of up-and-coming immune checkpoint inhibitors for pancreatic cancer

H Mahadevia, PLS Uson Junior, J Wang… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Immune checkpoint inhibitors (ICIs) targeting programmed cell
death protein-1 (PD-1/PD-L1) pathway as well as cytotoxic T-lymphocyte-associated protein …