Critical assessment of pan-genomic analysis of metagenome-assembled genomes

T Li, Y Yin - Briefings in Bioinformatics, 2022 - academic.oup.com
Pan-genome analyses of metagenome-assembled genomes (MAGs) may suffer from the
known issues with MAGs: fragmentation, incompleteness and contamination. Here, we …

[HTML][HTML] RIBAP: a comprehensive bacterial core genome annotation pipeline for pangenome calculation beyond the species level

K Lamkiewicz, LM Barf, K Sachse, M Hölzer - Genome Biology, 2024 - Springer
Microbial pangenome analysis identifies present or absent genes in prokaryotic genomes.
However, current tools are limited when analyzing species with higher sequence diversity or …

FrangiPANe, a tool for creating a panreference using left behind reads

TD Christine, C Clothilde, B Mathieu… - NAR Genomics and …, 2023 - academic.oup.com
We present here FrangiPANe, a pipeline developed to build panreference using short reads
through a map-then-assemble strategy. Applying it to 248 African rice genomes using an …

[HTML][HTML] PanDelos-frags: A methodology for discovering pangenomic content of incomplete microbial assemblies

V Bonnici, C Mengoni, M Mangoni, G Franco… - Journal of Biomedical …, 2023 - Elsevier
Pangenomics was originally defined as the problem of comparing the composition of genes
into gene families within a set of bacterial isolates belonging to the same species. The …

[HTML][HTML] 畜禽泛基因组研究进展

李珂, 王宇龙, 李栋, 史新娥, 杨公社, 于太永 - 畜牧兽医学报, 2023 - html.rhhz.net
泛基因组是近些年来基因组研究领域出现的一个新名词, 相较于单个线性参考基因组具有明显
优势, 能够有效解决参考基因组涵盖遗传信息有限的问题. 随着测序技术的发展和对基因组的 …

Pangenome calculation beyond the species level using RIBAP: A comprehensive bacterial core genome annotation pipeline based on Roary and pairwise ILPs

K Lamkiewicz, LM Barf, K Sachse, M Hölzer - bioRxiv, 2023 - biorxiv.org
Pangenome analysis is a computational method for identifying genes that are present or
absent from a group of genomes, which helps to understand evolutionary relationships and …

Critical assessment of pan-genomics of metagenome-assembled genomes

T Li, Y Yin - bioRxiv, 2022 - biorxiv.org
Background Large scale metagenome assembly and binning to generate metagenome-
assembled genomes (MAGs) has become possible in the past five years. As a result …

PANPROVA: pangenomic prokaryotic evolution of full assemblies

V Bonnici, R Giugno - Bioinformatics, 2022 - academic.oup.com
Motivation Computational tools for pangenomic analysis have gained increasing interest
over the past two decades in various applications such as evolutionary studies and vaccine …

A k-mer Based Sequence Similarity for Pangenomic Analyses

V Bonnici, A Cracco, G Franco - International Conference on Machine …, 2021 - Springer
In this work we propose an approach to improve the performance of a current methodology,
computing k-mer based sequence similarity via Jaccard index, for pangenomic analyses …

The differences of prokaryotic pan-genome analysis on complete genomes and simulated metagenome-assembled genomes

T Li - 2021 - digitalcommons.unl.edu
Metagenomic assembly is often used in microbiome research. In metagenomic assembly,
contigs are binned based on the shared nucleotide composition. These contig bins are …