Neuro-inflammation in pediatric traumatic brain injury—from mechanisms to inflammatory networks

E Fraunberger, MJ Esser - Brain sciences, 2019 - mdpi.com
Compared to traumatic brain injury (TBI) in the adult population, pediatric TBI has received
less research attention, despite its potential long-term impact on the lives of many children …

Biomarkers in moderate to severe pediatric traumatic brain injury: a review of the literature

JCM Pareja, X Li, N Gandham, KK Wang… - Pediatric …, 2022 - Elsevier
Background Despite decades of research, outcomes in pediatric traumatic brain injury (pTBI)
remain highly variable. Brain biofluid-specific biomarkers from pTBI patients may allow us to …

Functional, structural, and neurotoxicity biomarkers in integrative assessment of concussions

SA Dambinova, JC Maroon, AM Sufrinko… - Frontiers in …, 2016 - frontiersin.org
Concussion is a complex, heterogeneous process affecting the brain. Accurate assessment
and diagnosis and appropriate management of concussion are essential to ensure that …

Fluid biomarkers of chronic traumatic brain injury

S Friberg, C Lindblad, FA Zeiler, H Zetterberg… - Nature Reviews …, 2024 - nature.com
Traumatic brain injury (TBI) is a leading cause of long-term disability across the world.
Evidence for the usefulness of imaging and fluid biomarkers to predict outcomes and screen …

Prior traumatic brain injury is a risk factor for in-hospital mortality in moderate to severe traumatic brain injury: a TRACK-TBI cohort study

JK Yue, LL Etemad, MM Elguindy… - Trauma Surgery & …, 2024 - tsaco.bmj.com
Objectives An estimated 14–23% of patients with traumatic brain injury (TBI) incur multiple
lifetime TBIs. The relationship between prior TBI and outcomes in patients with moderate to …

Traumatic brain injury in the long-COVID era

DV Agoston - Neurotrauma Reports, 2024 - liebertpub.com
Major determinants of the biological background or reserve, such as age, biological sex,
comorbidities (diabetes, hypertension, obesity, etc.), and medications (eg, anticoagulants) …

Characterization of the antibody response after cervical spinal cord injury

A Ulndreaj, A Tzekou, AJ Mothe, AM Siddiqui… - Journal of …, 2017 - liebertpub.com
The immune system plays a critical and complex role in the pathobiology of spinal cord
injury (SCI), exerting both beneficial and detrimental effects. Increasing evidence suggests …

Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP+ B cells, neuropathology, and neurobehavioral …

J Iannucci, R Dominy, S Bandopadhyay… - Journal of …, 2024 - Springer
Background Traumatic brain injury (TBI) is a significant risk factor for Alzheimer's disease
(AD), and accumulating evidence supports a role for adaptive immune B and T cells in both …

Prognostic and diagnostic utility of serum biomarkers in pediatric traumatic brain injury

JC Munoz Pareja, JP de Rivero Vaccari… - Journal of …, 2024 - liebertpub.com
Traumatic brain injury (TBI) remains a major cause of morbidity and death among the
pediatric population. Timely diagnosis, however, remains a complex task because of the …

The role of autoimmunity in pituitary dysfunction due to traumatic brain injury

A De Bellis, G Bellastella, MI Maiorino, A Costantino… - Pituitary, 2019 - Springer
Purpose Traumatic brain injury (TBI) is one of the most common causes of mortality and long-
term disability and it is associated with an increased prevalence of neuroendocrine …