[HTML][HTML] Approaches to decrease hyperglycemia by targeting impaired hepatic glucose homeostasis using medicinal plants

G Mata-Torres, A Andrade-Cetto… - Frontiers in …, 2021 - frontiersin.org
Liver plays a pivotal role in maintaining blood glucose levels through complex processes
which involve the disposal, storage, and endogenous production of this carbohydrate …

[HTML][HTML] Reevaluating nutrition as a risk factor for cardio-metabolic diseases

P López-Jaramillo, J Otero, PA Camacho… - Colombia …, 2018 - scielo.org.co
Objective: Review published papers on the role of macro-nutrient intake in cardiovascular
risk. Results: Recent reports from the PURE study and several previous meta-analyses …

A proposed lectin‐mediated mechanism to explain the in Vivo antihyperglycemic activity of γ‐conglutin from Lupinus albus seeds

M Grácio, J Rocha, R Pinto… - Food Science & …, 2021 - Wiley Online Library
Experiments conducted in vitro and in vivo, as well as clinical trials for hypoglycemic
therapeutics, support the hypoglycemic properties of the lectin γ‐conglutin, a Lupinus seed …

[HTML][HTML] Antidiabetic effects and mechanisms of action of γ-conglutin from lupin seeds

M Tapadia, S Johnson, R Utikar, P Newsholme… - Journal of Functional …, 2021 - Elsevier
The glucose modulating properties of lupin have been attributed to its seed protein γ-
conglutin. Here we explored the antidiabetic potential of γ-conglutin purified from lupin …

Native food crops for present and future generations: Their role in nutrition and health

CCQ Ledezma - Sustainability of the food system, 2020 - Elsevier
Abstract The Andean and Amazonian regions harbor a remarkably rich biodiversity. Many
food crops such as corn, potato, cassava, tomato, peanut, and cacao have crossed borders …

Lupin γ-conglutin protects against cell death induced by oxidative stress and lipotoxicity, but transiently inhibits in vitro insulin secretion by increasing KATP channel …

TJ Guzmán, M Düfer, M Wiedemann… - International Journal of …, 2021 - Elsevier
Lupin γ-conglutin beneficially modulates glycemia, but whether it protects against oxidative
and lipotoxic damage remains unknown. Here, we studied the effects of γ-conglutin on cell …

Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 …

M Tapadia, R Carlessi, S Johnson, R Utikar… - Molecular and cellular …, 2019 - Elsevier
Lupin seed proteins have been reported to exhibit hypoglycaemic effects in animals and
humans following oral administration, however little is known about its mechanism of action …

The micronutrient content in underutilized crops: the Lupinus mutabilis sweet case

M Vera-Vega, J Jimenez-Davalos, G Zolla - Scientific Reports, 2022 - nature.com
Adequate intake of micronutrients is necessary to reduce widespread health issues linked to
low intake of iron (Fe), zinc (Zn), boron (B), copper (Cu), and manganese (Mn). Because …

Alkaline extraction–isoelectric precipitation of plant proteins

I Cruz-Solis, CC Ibarra-Herrera… - … from Plants: Novel …, 2023 - Springer
Alkaline extraction–isoelectric precipitation has been the most used method to extract
protein from plant foods. The sample preparation will depend on the features of the starting …

In vitro and in silico studies of antioxidant peptides from tarwi (Lupinus mutabilis) as inhibitors of angiotensin‐converting enzyme and dipeptidyl peptidase IV …

R Chirinos, TV de Oliveira, F Guzmán… - … Journal of Food …, 2023 - Wiley Online Library
The present research aimed to evaluate three peptides synthesised from tarwi: AVPFWM,
YSGWLGL and AHAGFGMLY in their antioxidant, antihypertensive and hypoglycemic …