[HTML][HTML] A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics

NM Riley, CR Bertozzi, SJ Pitteri - Molecular & Cellular Proteomics, 2021 - ASBMB
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Chemoenzymatic methods for the synthesis of glycoproteins

C Li, LX Wang - Chemical reviews, 2018 - ACS Publications
Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

Green solvents in carbohydrate chemistry: from raw materials to fine chemicals

A Farrán, C Cai, M Sandoval, Y Xu, J Liu… - Chemical …, 2015 - ACS Publications
In recent decades, there has been an increasing effort to reduce the use of fossil fuels and
oil derivatives, to decrease environmental pollution, and to counteract global warming. The …

[HTML][HTML] Implications of glycosylation in Alzheimer's disease

H Haukedal, KK Freude - Frontiers in Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of dementia, affecting millions of
people worldwide, and no cure is currently available. The major pathological hallmarks of …

Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications

H Leemhuis, T Pijning, JM Dobruchowska… - Journal of …, 2013 - Elsevier
Glucansucrases are extracellular enzymes that synthesize a wide variety of α-glucan
polymers and oligosaccharides, such as dextran. These carbohydrates have found …

β-Galactosidases: A great tool for synthesizing galactose-containing carbohydrates

L Lu, L Guo, K Wang, Y Liu, M Xiao - Biotechnology advances, 2020 - Elsevier
Abstract β-Galactosidases, an important class of glycosidases, naturally catalyze the
hydrolysis of β-galactosidic bonds in oligosaccharides and polysaccharides. Traditionally …

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts

T Desmet, W Soetaert, P Bojarová… - … A European Journal, 2012 - Wiley Online Library
Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

[HTML][HTML] Microbial beta glucosidase enzymes: recent advances in biomass conversation for biofuels application

N Srivastava, R Rathour, S Jha, K Pandey… - Biomolecules, 2019 - mdpi.com
The biomass to biofuels production process is green, sustainable, and an advanced
technique to resolve the current environmental issues generated from fossil fuels. The …

A novel class of α-glucosidase and HMG-CoA reductase inhibitors from Ganoderma leucocontextum and the anti-diabetic properties of ganomycin I in KK-Ay mice

K Wang, L Bao, K Ma, J Zhang, B Chen, J Han… - European Journal of …, 2017 - Elsevier
Three new meroterpenoids, ganoleucin AC (1–3), together with five known meroterpenoids
(4–8), were isolated from the fruiting bodies of Ganoderma leucocontextum. The structures …

Glycoside hydrolases: catalytic base/nucleophile diversity

TV Vuong, DB Wilson - Biotechnology and bioengineering, 2010 - Wiley Online Library
Recent studies have shown that a number of glycoside hydrolase families do not follow the
classical catalytic mechanisms, as they lack a typical catalytic base/nucleophile. A variety of …