Binge-eating disorder is characterized by excessive, uncontrollable consumption of
palatable food within brief periods of time. The role of the glutamatergic N-methyl-D …

Background Adolescent and adult rats emit 50-kHz ultrasonic vocalizations (USVs) to
communicate the appetitive arousal and the presence of positive emotional states to …

In this article, we review studies of genetic moderators of the response to medications to
treat alcohol dependence, the acute response to alcohol, and the response to the …

Background There is growing debate on the use of drugs that promote cognitive
enhancement. Amphetamine-like drugs have been employed as cognitive enhancers, but …

Glutamatergic system has an important role in cocaine-seeking behavior. Studies have
reported that chronic exposure to cocaine induces downregulation of glutamate transporter …

The incidence of Parkinson's disease (PD), the second most common neurodegenerative
disorder, has increased exponentially as the global population continues to age. Although …

The purpose of this review is to present up-to-date pharmacological, genetic, and behavioral
findings from the alcohol-preferring P rat and summarize similar past work. Behaviorally, the …

Obesity is a multifactorial disease, which in turn contributes to the onset of comorbidities,
such as diabetes and atherosclerosis. Moreover, there are only few options available for …

Background Alcohol dependence (AD) shows evidence for genetic liability, but genes
influencing risk remain largely unidentified. Methods We conducted a genomewide …

Emerging evidence indicates that many aspects of alcohol and drug dependence involve
changes in glutamate transmission. A number of studies have reported that drugs of abuse …