[HTML][HTML] Diverse roles of heterogeneous nuclear ribonucleoproteins in viral life cycle

K Bhattarai, M Holcik - Frontiers in Virology, 2022 - frontiersin.org
Understanding the host-virus interactions helps to decipher the viral replication strategies
and pathogenesis. Viruses have limited genetic content and rely significantly on their host …

The A-rich RNA sequences of HIV-1 pol are important for the synthesis of viral cDNA

CP Keating, MK Hill, DJ Hawkes, RP Smyth… - Nucleic acids …, 2009 - academic.oup.com
The bias of A-rich codons in HIV-1 pol is thought to be a record of hypermutations in viral
genomes that lack biological functions. Bioinformatic analysis predicted that A-rich …

[HTML][HTML] Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition

Y Liu, A Abula, H Xiao, H Guo, T Li, L Zheng… - Journal of Molecular …, 2023 - Elsevier
Heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP A2/B1) has been identified as a
nuclear DNA sensor. Upon viral infection, hnRNP A2/B1 recognizes pathogen-derived DNA …

Distinct intracellular trafficking of equine infectious anemia virus and human immunodeficiency virus type 1 Gag during viral assembly and budding revealed by …

J Jin, T Sturgeon, C Chen, SC Watkins… - Journal of …, 2007 - Am Soc Microbiol
Retroviral Gag polyproteins are necessary and sufficient for virus budding. Numerous
studies of human immunodeficiency virus type 1 (HIV-1) Gag assembly and budding …

A novel, fully spliced, accessory gene in equine lentivirus with distinct rev-responsive element

X Zhang, J Li, M Zhang, B Bai, W Ma, Y Lin… - Journal of …, 2022 - Am Soc Microbiol
All lentiviruses encode the accessory protein Rev, whose main biological function is to
mediate the nuclear export of unspliced and incompletely spliced viral transcripts by binding …

Ty3 nucleocapsid controls localization of particle assembly

LSZ Larsen, N Beliakova-Bethell, V Bilanchone… - Journal of …, 2008 - Am Soc Microbiol
Expression of the budding yeast retrotransposon Ty3 results in production of viruslike
particles (VLPs) and retrotransposition. The Ty3 major structural protein, Gag3, similar to …

[HTML][HTML] Heterogeneous ribonucleoprotein A1 (hnRNPA1) interacts with the nucleoprotein of the influenza a virus and impedes virus replication

R Kaur, J Batra, O Stuchlik, MS Reed, J Pohl… - Viruses, 2022 - mdpi.com
Influenza A virus (IAV), like other viruses, depends on the host cellular machinery for
replication and production of progeny. The relationship between a virus and a host is …

In vitro dimerization of human immunodeficiency virus type 1 (HIV-1) spliced RNAs

L Sinck, D Richer, J Howard, M Alexander, DFJ Purcell… - Rna, 2007 - rnajournal.cshlp.org
The human immunodeficiency virus type 1 (HIV-1) packages its genomic RNA as a dimer of
homologous RNA molecules that has to be selected among a multitude of cellular and viral …

[HTML][HTML] IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis

Z Zhang, W Trypsteen, M Blaauw, X Chu, S Rutsaert… - BMC medicine, 2021 - Springer
Background Combination antiretroviral treatment (cART) cannot eradicate HIV-1 from the
body due to the establishment of persisting viral reservoirs which are not affected by therapy …

Sequence requirements for localization and packaging of Ty3 retroelement RNA

K Clemens, V Bilanchone, N Beliakova-Bethell… - Virus research, 2013 - Elsevier
Retroviruses and retrotransposons package genomic RNA into virus-like particles (VLPs) in
a poorly understood process. Expression of the budding yeast retrotransposon Ty3 results in …