[HTML][HTML] The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions

BH Gan, J Gaynord, SM Rowe, T Deingruber… - Chemical Society …, 2021 - pubs.rsc.org
Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

Multifunctional antimicrobial materials: From rational design to biomedical applications

S Duan, R Wu, YH Xiong, HM Ren, C Lei… - Progress in Materials …, 2022 - Elsevier
Though the history of mankind, we are strongly fighting with infected diseases that are
induced by bacteria, fungi, viruses, and other pathogens. Although a variety of medicines …

Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Multifunctional silk fibroin methacryloyl microneedle for diabetic wound healing

G Guan, Q Zhang, Z Jiang, J Liu, J Wan, P Jin, Q Lv - Small, 2022 - Wiley Online Library
Diabetic wound is one of the common complications in diabetic patients, which exhibits
chronic, hard‐to‐heal characteristics. The healing process of wounds is impaired by several …

Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Advances of Antimicrobial Peptide‐Based Biomaterials for the Treatment of Bacterial Infections

G Li, Z Lai, A Shan - Advanced Science, 2023 - Wiley Online Library
Owing to the increase in multidrug‐resistant bacterial isolates in hospitals globally and the
lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have …

Antibacterial quaternary ammonium agents: Chemical diversity and biological mechanism

W Dan, J Gao, X Qi, J Wang, J Dai - European Journal of Medicinal …, 2022 - Elsevier
Bacterial infections have seriously threatened public health especially with the increasing
resistance and the cliff-like decline of the number of newly approved antibacterial agents …

[HTML][HTML] Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms

T Vanzolini, M Bruschi, AC Rinaldi, M Magnani… - International Journal of …, 2022 - mdpi.com
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …

[HTML][HTML] Rational integration of defense and repair synergy on PEEK osteoimplants via biomimetic peptide clicking strategy

M Li, J Bai, H Tao, L Hao, W Yin, X Ren, A Gao, N Li… - Bioactive Materials, 2022 - Elsevier
Polyetheretherketone (PEEK) has been widely used as orthopedic and dental materials due
to excellent mechanical and physicochemical tolerance. However, its biological inertness …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …