Thermal immuno-nanomedicine in cancer
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
[HTML][HTML] Roles of CD4+ T cells as mediators of antitumor immunity
DS Kravtsov, AK Erbe, PM Sondel… - Frontiers in …, 2022 - frontiersin.org
It has been well established that CD8+ T cells serve as effector cells of the adaptive immune
response against tumors, whereas CD4+ T cells either help or suppress the generation of …
response against tumors, whereas CD4+ T cells either help or suppress the generation of …
[HTML][HTML] In-situ cryo-immune engineering of tumor microenvironment with cold-responsive nanotechnology for cancer immunotherapy
Cancer immunotherapy that deploys the host's immune system to recognize and attack
tumors, is a promising strategy for cancer treatment. However, its efficacy is greatly restricted …
tumors, is a promising strategy for cancer treatment. However, its efficacy is greatly restricted …
Liquid metal microparticles phase change medicated mechanical destruction for enhanced tumor cryoablation and dual‐mode imaging
Mechanical forces are crucial for normal living organisms as well as formation of tumor
microenvironments. However, to date, there are rather limited trials to regulate the …
microenvironments. However, to date, there are rather limited trials to regulate the …
[HTML][HTML] Hyperthermia targeting the tumor microenvironment facilitates immune checkpoint inhibitors
Z Li, J Deng, J Sun, Y Ma - Frontiers in Immunology, 2020 - frontiersin.org
Immune checkpoint inhibitors (ICIs) have ushered in a new era of cancer therapy; however,
ICIs are only effective in selective patients. The efficacy of ICIs is closely related to the tumor …
ICIs are only effective in selective patients. The efficacy of ICIs is closely related to the tumor …
[HTML][HTML] Microwave ablation induces Th1-type immune response with activation of ICOS pathway in early-stage breast cancer
W Zhou, M Yu, H Pan, W Qiu, H Wang… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Despite great advances in the treatment of breast cancer, innovative
approaches are still needed to reduce metastasis. As a minimally invasive local therapy (not …
approaches are still needed to reduce metastasis. As a minimally invasive local therapy (not …
[HTML][HTML] Immunomodulatory effect of locoregional therapy in the tumor microenvironment
L Xie, Z Meng - Molecular Therapy, 2023 - cell.com
Cancer immunotherapy appears to be a promising treatment option; however, only a subset
of patients with cancer responds favorably to treatment. Locoregional therapy initiates a …
of patients with cancer responds favorably to treatment. Locoregional therapy initiates a …
Programmed Upregulation of HSP70 by Metal‐Organic Frameworks Nanoamplifier for Enhanced Microwave Thermal‐Immunotherapy
W Guo, M Niu, Z Chen, Q Wu, L Tan… - Advanced …, 2022 - Wiley Online Library
Thermotherapy can directly kill tumor cells whilst being accompanied by immune‐enhancing
effects. However, this immune‐enhancing effect suffers from insufficient expression of …
effects. However, this immune‐enhancing effect suffers from insufficient expression of …
[HTML][HTML] Amplifying cancer treatment: advances in tumor immunotherapy and nanoparticle-based hyperthermia
Y Zhang, Z Li, Y Huang, B Zou, Y Xu - Frontiers in Immunology, 2023 - frontiersin.org
In the quest for cancer treatment modalities with greater effectiveness, the combination of
tumor immunotherapy and nanoparticle-based hyperthermia has emerged as a promising …
tumor immunotherapy and nanoparticle-based hyperthermia has emerged as a promising …
[HTML][HTML] Immunotherapeutic potential of T memory stem cells
Y Li, D Wu, X Yang, S Zhou - Frontiers in oncology, 2021 - frontiersin.org
Memory T cells include T memory stem cells (TSCM) and central memory T cells (TCM).
Compared with effector memory T cells (TEM) and effector T cells (TEFF), they have better …
Compared with effector memory T cells (TEM) and effector T cells (TEFF), they have better …