Background There is a need to develop surrogates for treatment efficacy in the neoadjuvant
setting to speed-up drug development and stratify patients according to outcome. Preclinical …

Programmed death ligand 1 (PD-L1) expression by tumor-infiltrating lymphocytes (TILs) and
tumor cells in breast cancer has been reported, but the relationships between PD-L1 …

Immunotherapy provides the best approach to reduce the high mortality of metastatic breast
cancer (BC). We demonstrate a chemo-immunotherapy approach, which utilizes a liposomal …

Abstract Programmed death 1 ligand 1 (PD-L1) is an immune regulatory molecule that limits
antitumor immune activity. Targeting of PD-L1 and other immune checkpoint proteins has …

Background Because immune responses within the tumor microenvironment are important
predictors of tumor biology, correlations of types of tumor infiltrating lymphocytes (TILs) with …

Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral
part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer …

Simple Summary The histopathological image is widely considered as the gold standard for
the diagnosis and prognosis of human cancers. Recently, deep learning technology has …

Triple-negative breast cancer (TNBC) is a high-risk malignancy due to its high capacity for
invasion and lack of targeted therapy. Immunotherapy continues to demonstrate efficacy in a …

Nanoscience has long been lauded as a method through which tumor-associated barriers
could be overcome. As successful as cancer immunotherapy has been, limitations …

Background The prognostic values of tumor-infiltrating lymphocytes (TILs) and TILs subsets
in breast cancer (BC) are uncertain. Methods A systematic literature search (MEDLINE, Web …