Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …

Background Inflammatory bowel disease (IBD) constitutes a group of auto-inflammatory
disorders that impact the gastrointestinal tract and other systemic organs. The gut …

Microbial communities are shaped by viral predators. Yet, resolving which viruses (phages)
and bacteria are interacting is a major challenge in the context of natural levels of microbial …

Bacteriophages are viruses that infect bacteria or archaea. Understanding the diverse and
intricate genomic architectures of phages is essential to study microbial ecosystems and …

Phage satellites are bacterial genetic elements that co-opt phage machinery for their own
dissemination. Here we identify a family of satellites, named Phage-Inducible Chromosomal …

The characterization of therapeutic phage genomes plays a crucial role in the success rate
of phage therapies. There are three checkpoints that need to be examined for the selection …

Nowadays, bacteriophages are increasingly considered as an alternative treatment for a
variety of bacterial infections in cases where classical antibiotics have become ineffective …

Viral genomes are poorly annotated in metagenomic samples, representing an obstacle to
understanding viral diversity and function. Current annotation approaches rely on alignment …

Eukaryotic genomes are known to have garnered innovations from both archaeal and
bacterial domains but the sequence of events that led to the complex gene repertoire of …

Asgard archaea are globally distributed prokaryotic microorganisms related to eukaryotes;
however, viruses that infect these organisms have not been described. Here, using …