Discovering drugs for the treatment of Ebola virus

SL Bixler, AJ Duplantier, S Bavari - Current Treatment Options in Infectious …, 2017 - Springer
Opinion statement Purpose of review Ebola virus, a member of the Filoviridae family, is a
causative agent of severe viral hemorrhagic fever in humans. Over the past 40 years, the …

Mathematical model of Ebola transmission dynamics with relapse and reinfection

FB Agusto - Mathematical biosciences, 2017 - Elsevier
The Ebola virus disease is caused by the Ebola virus which belongs to the filoviridae virus
family. The 2014 outbreaks were estimated to have caused over 11,000 fatalities. In this …

Insights from clinical research completed during the west Africa Ebola virus disease epidemic

A Rojek, P Horby, J Dunning - The Lancet Infectious Diseases, 2017 - thelancet.com
Summary The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale.
Now that the epidemic has ended, it is a relevant time to examine published studies with …

[HTML][HTML] Clinical, virological, and biological parameters associated with outcomes of Ebola virus infection in Macenta, Guinea

MA Vernet, S Reynard, A Fizet, J Schaeffer… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. The pathogenesis of Ebola virus (EBOV) disease (EVD) is poorly
characterized. The establishment of well-equipped diagnostic laboratories close to Ebola …

Reflections on the Ebola public health emergency of international concern, part 2: the unseen epidemic of posttraumatic stress among health-care personnel and …

L Paladino, RP Sharpe, SC Galwankar… - Journal of global …, 2017 - journals.lww.com
Neither dramatic footage nor horrifying statistics from the most recent Ebola virus (EBOV)
outbreak come close to reflecting the true impact of the EBOV disease (EVD) on affected …

Ebola virus ribonucleic acid detection in semen more than two years after resolution of acute Ebola virus infection

WA Fischer, J Brown, DA Wohl, AJ Loftis… - Open forum …, 2017 - academic.oup.com
Among 149 men who survived Ebola virus disease (EVD) and donated semen 260–1016
days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%) …

[HTML][HTML] Ebola and its control in Liberia, 2014–2015

TG Nyenswah, F Kateh, L Bawo… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
An early priority for directing the response was surveillance. Using WHO case definitions for
suspected, probable, and confirmed cases, the 15 counties of Liberia reported Ebola cases …

Persistence of Ebola virus after the end of widespread transmission in Liberia: an outbreak report

EK Dokubo, A Wendland, SE Mate… - The Lancet Infectious …, 2018 - thelancet.com
Background Outbreak response efforts for the 2014–15 Ebola virus disease epidemic in
west Africa brought widespread transmission to an end. However, subsequent clusters of …

Reduced evolutionary rate in reemerged Ebola virus transmission chains

DJ Blackley, MR Wiley, JT Ladner, M Fallah, T Lo… - Science …, 2016 - science.org
On 29 June 2015, Liberia's respite from Ebola virus disease (EVD) was interrupted for the
second time by a renewed outbreak (“flare-up”) of seven confirmed cases. We demonstrate …

Ocular complications in survivors of the Ebola outbreak in Guinea

E Hereth-Hebert, MO Bah, JF Etard, MS Sow… - American journal of …, 2017 - Elsevier
Purpose The Ebola outbreak of 2013–2016 severely affected West Africa and resulted in
2544 deaths and 1270 survivors in Guinea, the country where it began. This Ebola virus was …