Cancer remains to be one of the leading causes of death in the United States and around
the world. The advent of modern drug-targeted therapies has undeniably improved cancer …

Gallic acid, a predominant polyphenol, has been shown to inhibit carcinogenesis in animal
models and in vitro cancerous cell lines. The inhibitory effect of gallic acid on cancer cell …

It is well admitted that the link between chronic inflammation and cancer involves cytokines
and mediators of inflammatory pathways, which act during the different steps of …

Growing evidence indicates that inflammation is a contributing factor leading to cancer
development. However, pathways involved in this progression are not well understood. To …

Omega-6 (ω-6) polyunsaturated fatty acids (PUFA), abundant in the Western diet, are
precursors for a number of key mediators of inflammation including the 2-series of …

Linoleic and alpha-linolenic acids, obtained from plant material in the diet are the precursors
in tissues of two families with opposing effects which are referred to as “essential fatty …

Colorectal cancer is the third common cancer in this world, accounting for more than 1
million cases each year. However, detailed etiology and mechanism of colorectal cancer …

Photodynamic therapy (PDT) involves the administration of a photosensitizer (PS) followed
by illumination with visible light, leading to generation of reactive oxygen species. The …

Cyclooxygenase (COX), a key enzyme in the prostanoid biosynthetic pathway, has received
considerable attention due to its role in human cancers. Observational and randomized …

Lipid bodies (lipid droplets) are emerging as dynamic organelles involved in lipid
metabolism and inflammation. Increased lipid body numbers have been described in tumor …