Intelligence is a core construct in differential psychology and behavioural genetics, and
should be so in cognitive neuroscience. It is one of the best predictors of important life …

Methods: We conducted a literature search (2005-2020) using online database PubMed,
specifically for studies related to the clinical aspects of intellectual disability as they apply to …

Background Whole-exome sequencing has transformed gene discovery and diagnosis in
rare diseases. Translation into disease-modifying treatments is challenging, particularly for …

Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autism
spectrum disorder and intellectual disability; however, the neurobiological basis for this is …

Because of the unbalanced sex ratio (1.3–1.4 to 1) observed in intellectual disability (ID) and
the identification of large ID-affected families showing X-linked segregation, much attention …

Intellectual disability (ID) occurs in almost 3% of newborns. Despite substantial research, a
fundamental question about its origin and links to intelligence (IQ) still remains. ID has been …

Most severe forms of intellectual disability (ID) have specific genetic causes. Numerous X
chromosome gene defects and disease-causing copy-number variants have been linked to …

X-linked intellectual disability (XLID) is a genetically heterogeneous disorder with more than
100 genes known to date. Most genes are responsible for a small proportion of patients only …

Developmental approaches provide inclusive, universal, and methodologically rigorous
frameworks for studying persons with intellectual disability (ID). This is an exceptionally …

tRNAs are short noncoding RNAs required for protein translation. The human genome
includes more than 600 putative tRNA genes, many of which are considered redundant …