Glaucoma is a progressive, age-related optic neuropathy and a leading cause of irreversible
blindness in the world. Animal models of glaucoma are essential to our continued efforts of …

Numerous clinical studies have revealed the utility of circulating AM (adrenomedullin) or MR-
proAM (mid-regional proAM 45-92) as an effective prognostic and diagnostic biomarker for a …

Glaucoma, one of the leading causes of irreversible blindness worldwide, is a complex and
heterogenous disease. While environmental factors are important, it is well-recognized that …

Primary angle-closure glaucoma (PACG) is estimated to affect over 30 million people
worldwide by 2040 and is highly prevalent in the Asian population. PACG is more severe …

Adrenomedullin (AM) and its receptor complexes, calcitonin receptor-like receptor (Calcrl)
and receptor activity modifying protein 2/3, are highly expressed in lymphatic endothelial …

Cerebral blood flow autoregulation (CA) shifts to higher blood pressures in chronic
hypertensive patients, which increases their risk for brain damage. Although cerebral …

Glaucoma is a group of heterogeneous optic neuropathy and is the second leading cause of
irreversible blindness worldwide. The two most common clinical types of glaucoma include …

We report on the functional optical coherence tomography (OCT) imaging of iris tissue
morphology and microcirculation in living small animals. Anterior segments of healthy …

Glaucoma is a group of progressive optic neuropathies, characterized by the degeneration
of retinal ganglion cells related to the level of intraocular pressure and other factors. The …

Purpose To determine whether the polymorphisms of calcitonin receptor-like receptor gene
(CALCRL) are associated with primary angle closure glaucoma (PACG) in a southern …