Recent advances in biopolymer-based hydrogels and their potential biomedical applications

DK Patel, E Jung, S Priya, SY Won, SS Han - Carbohydrate polymers, 2023 - Elsevier
Hydrogels are three-dimensional networks of polymer chains containing large amounts of
water in their structure. Hydrogels have received significant attention in biomedical …

Multifunctional systems based on nano-in-microparticles as strategies for drug delivery: advances, challenges, and future perspectives

SG Carvalho, AM Dos Santos… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Innovative delivery systems are a promising and attractive approach for drug
targeting in pharmaceutical technology. Among the various drug delivery systems studied …

Chitosan as a Polyfunctional Crosslinker for a Renewable-Based Resorcinol Diglycidyl Ether

I Fusteş-Dămoc, T Măluţan… - … Sustainable Chemistry & …, 2023 - ACS Publications
Chitosan is an abundant renewable biopolymer, insufficiently valorized, which is suitable for
the development of sustainable and fully biobased materials. In this study, we combined it …

Resveratrol-loaded sulfated Hericium erinaceus β-glucan-chitosan nanoparticles: Preparation, characterization and synergistic anti-inflammatory effects

Z Zhang, M Ge, D Wu, W Li, W Chen, P Liu… - Carbohydrate …, 2024 - Elsevier
Resveratrol (RES) is a natural polyphenol with excellent biological activity. But the poor
stability and bioavailability of RES severely limit its application. Thus, the resveratrol-loaded …

Chitosan surface modification modulates the mucoadhesive, permeation and anti-angiogenic properties of gellan gum/bevacizumab nanoparticles

SG Carvalho, FF Haddad, AM Dos Santos… - International Journal of …, 2024 - Elsevier
Bevacizumab (BVZ) was the first monoclonal antibody approved by the FDA and has shown
an essential advance in the antitumor therapy of colorectal cancer (CRC), however, the …

Investigation of cellular uptake and transport capacity of Cordyceps sinensis exopolysaccharide‑selenium nanoparticles with different particle sizes in Caco-2 cell …

X Zhang, Y Xiao, Q Huang - International Journal of Biological …, 2024 - Elsevier
Cordyceps sinensis exopolysaccharide‑selenium nanoparticles (EPS-SeNPs) were
successfully constructed, characterized, and its Se release kinetics and mechanism were …

The Current and Promising Oral Delivery Methods for Protein-and Peptide-Based Drugs

M Nicze, M Borówka, A Dec, A Niemiec… - International Journal of …, 2024 - mdpi.com
Drugs based on peptides and proteins (PPs) have been widely used in medicine, beginning
with insulin therapy in patients with diabetes mellitus over a century ago. Although the oral …

Research progress of polysaccharide-gold nanocomplexes in drug delivery

M Song, A Aipire, E Dilxat, J Li, G Xia, Z Jiang, Z Fan… - Pharmaceutics, 2024 - mdpi.com
Clinical drug administration aims to deliver drugs efficiently and safely to target tissues,
organs, and cells, with the objective of enabling their therapeutic effects. Currently, the main …

The carrier function and inhibition effect on benign prostatic hyperplasia of a glucan from Epimedium brevicornu Maxim

L Yan, B Huang, X Wang, Y Jiang, J Liu, X Jia… - Carbohydrate …, 2024 - Elsevier
Epimedium, a traditional Chinese medicine commonly used as a dietary supplement,
contains polysaccharides and flavonoids as its main bioactive ingredients. In this study, a …

Effect of hydroxyethyl starch on drug stability and release of semaglutide in PLGA microspheres

H Zeng, J Song, Y Li, C Guo, Y Zhang, T Yin… - International Journal of …, 2024 - Elsevier
The degradation of peptide drugs limits the application of peptide drug microspheres.
Structural changes of peptides at the water–oil interface and the destruction of their spatial …