A review of the pangenome: how it affects our understanding of genomic variation, selection and breeding in domestic animals?
Y Gong, Y Li, X Liu, Y Ma, L Jiang - Journal of Animal Science and …, 2023 - Springer
As large-scale genomic studies have progressed, it has been revealed that a single
reference genome pattern cannot represent genetic diversity at the species level. While …
reference genome pattern cannot represent genetic diversity at the species level. While …
Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes
P Kalds, S Zhou, Y Gao, B Cai, S Huang… - Genetics Selection …, 2022 - Springer
Background After domestication, the evolution of phenotypically-varied sheep breeds has
generated rich biodiversity. This wide phenotypic variation arises as a result of hidden …
generated rich biodiversity. This wide phenotypic variation arises as a result of hidden …
Whole-body adipose tissue multi-omic analyses in sheep reveal molecular mechanisms underlying local adaptation to extreme environments
YX Xu, B Wang, JN Jing, R Ma, YH Luo, X Li… - Communications …, 2023 - nature.com
The fat tail of sheep is an important organ that has evolved to adapt to extreme
environments. However, the genetic mechanisms underlying the fat tail phenotype remain …
environments. However, the genetic mechanisms underlying the fat tail phenotype remain …
In it for the long run: perspectives on exploiting long-read sequencing in livestock for population scale studies of structural variants
TV Nguyen, CJ Vander Jagt, J Wang… - Genetics Selection …, 2023 - Springer
Studies have demonstrated that structural variants (SV) play a substantial role in the
evolution of species and have an impact on Mendelian traits in the genome. However, unlike …
evolution of species and have an impact on Mendelian traits in the genome. However, unlike …
[PDF][PDF] Pangenome obtained by long-read sequencing of 11 genomes reveal hidden functional structural variants in pigs
YF Jiang, S Wang, CL Wang, RH Xu, WW Wang… - Iscience, 2023 - cell.com
Long-read sequencing (LRS) facilitates both the genome assembly and the discovery of
structural variants (SVs). Here, we built a graph-based pig pangenome by incorporating 11 …
structural variants (SVs). Here, we built a graph-based pig pangenome by incorporating 11 …
Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed
DK Lagler, E Hannemann, K Eck, J Klawatsch… - Communications …, 2022 - nature.com
Docking the tails of lambs in long-tailed sheep breeds is a common practice worldwide. But
this practice is associated with pain. Breeding for a shorter tail could offer an alternative …
this practice is associated with pain. Breeding for a shorter tail could offer an alternative …
Genetic Basis of Dorper Sheep (Ovis aries) Revealed by Long-Read De Novo Genome Assembly
G Qiao, P Xu, T Guo, Y Wu, X Lu, Q Zhang, X He… - Frontiers in …, 2022 - frontiersin.org
Dorper sheep (Ovis aries)(DPS), developed in the 1930s by crossing Dorset Horn and
Blackhead Persian sheep in South Africa, is a world-famous composite breed for mutton …
Blackhead Persian sheep in South Africa, is a world-famous composite breed for mutton …
Developmental regulation of conserved non-coding element evolution provides insights into limb loss in squamates
Limb loss shows recurrent phenotypic evolution across squamate lineages. Here, based on
three de novo-assembled genomes of limbless lizards from different lineages, we showed …
three de novo-assembled genomes of limbless lizards from different lineages, we showed …
Initial analysis of structural variation detections in cattle using Long-read sequencing methods
Structural variations (SVs), as a great source of genetic variation, are widely distributed in
the genome. SVs involve longer genomic sequences and potentially have stronger effects …
the genome. SVs involve longer genomic sequences and potentially have stronger effects …
Newly reported 90-bp deletion within the ovine BMPRIB gene: Does it widely distribute, link to the famous FecB (p. Q249R) mutation, and affect litter size?
Z Akhatayeva, C Cao, Y Huang, Q Zhou, Q Zhang… - Theriogenology, 2022 - Elsevier
The study of the BMPRIB gene polymorphisms has become of great importance in sheep,
because it provides critical genetic tools to improve reproductive efficiency in ewes. The …
because it provides critical genetic tools to improve reproductive efficiency in ewes. The …