Riding the wave of ependymal cilia: genetic susceptibility to hydrocephalus in primary ciliary dyskinesia

L Lee - Journal of neuroscience research, 2013 - Wiley Online Library
Congenital hydrocephalus is a relatively common and debilitating birth defect with several
known physiological causes. Dysfunction of motile cilia on the ependymal cells that line the …

[HTML][HTML] Mechanisms of cerebrospinal fluid and brain interstitial fluid production

J Xiang, Y Hua, G Xi, RF Keep - Neurobiology of disease, 2023 - Elsevier
Fluid homeostasis is fundamental for brain function with cerebral edema and hydrocephalus
both being major neurological conditions. Fluid movement from blood into brain is one …

[HTML][HTML] Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1

TL Toft-Bertelsen, D Barbuskaite, EK Heerfordt… - Fluids and barriers of the …, 2022 - Springer
Background A range of neurological pathologies may lead to secondary hydrocephalus.
Treatment has largely been limited to surgical cerebrospinal fluid (CSF) diversion, as …

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus

AK Singh, G Allington, S Viviano, S McGee, E Kiziltug… - Brain, 2024 - academic.oup.com
Hydrocephalus, characterized by cerebral ventriculomegaly, is the most common disorder
requiring brain surgery in children. Recent studies have implicated SMARCC1, a component …

Current state and future development of intracranial neuroendoscopic surgery

G Cinalli, P Cappabianca, R De Falco… - Expert review of …, 2005 - Taylor & Francis
Since the introduction of the modern, smaller endoscopes in the 1960s, neuroendoscopy
has become an expanding field of neurosurgery. Neuroendoscopy reflects the tendency of …

Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice

A Feldner, MG Adam, F Tetzlaff, I Moll… - EMBO molecular …, 2017 - embopress.org
Hydrocephalus is a common congenital anomaly. LCAM 1 and MPDZ (MUPP 1) are the only
known human gene loci associated with non‐syndromic hydrocephalus. To investigate …

Endoscopic third ventriculostomy in the treatment of hydrocephalus in pediatric patients

C Di Rocco, G Cinalli, L Massimi, P Spennato… - Advances and technical …, 2006 - Springer
Advances in surgical instrumentation and technique have lead to an extensive use of
endoscopic third ventriculostomy in the management of pediatric hydrocephalus. The aim of …

Muscle ultrasound

S Pillen, A Boon, N Van Alfen - Handbook of Clinical Neurology, 2016 - Elsevier
Muscle ultrasound is an ideal imaging modality that allows for noninvasive, radiation-free
point-of-care neuromuscular imaging. There are many potential applications of muscle …

Neuroendoscopic treatment of arachnoid cysts of the quadrigeminal cistern: a series of 14 cases

G Cinalli, P Spennato, L Columbano… - Journal of …, 2010 - thejns.org
Object In this paper, the authors' goal was to evaluate the role of neuroendoscopy in the
treatment of arachnoid cysts of the quadrigeminal cistern. Methods Between March 1995 …

LPA1/3 overactivation induces neonatal posthemorrhagic hydrocephalus through ependymal loss and ciliary dysfunction

NC Lummis, P Sánchez-Pavón, G Kennedy… - Science …, 2019 - science.org
Posthemorrhagic hydrocephalus (PHH) in premature infants is a common neurological
disorder treated with invasive neurosurgical interventions. Patients with PHH lack effective …