Metabolic reprogramming in cancer is not only a biological hallmark but also reveals
treatment vulnerabilities. Numerous metabolic molecules have shown promise as treatment …

In the decade after being awarded the Nobel Prize in Chemistry in 2002, matrix-assisted
laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been …

Timely screening of neuromyelitis optica spectrum disorder (NMOSD) and differential
diagnosis from myelin oligodendrocyte glycoprotein associated disorder (MOGAD) are the …

Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …

Cancer exerts a multitude of effects on metabolism, including the reprogramming of cellular
metabolic pathways and alterations in metabolites that facilitate inappropriate proliferation of …

Epithelial ovarian cancer (EOC) is a polyfactorial process associated with alterations in
metabolic pathways. A high‐performance screening tool for EOC is in high demand to …

Objective Metabolic biomarkers are expected to decode the phenotype of gastric cancer
(GC) and lead to high-performance blood tests towards GC diagnosis and prognosis. We …

Polycystic ovary syndrome (PCOS) is a common endocrine disease regulated by metabolic
disorders, the effective intervention of which depends on diverse phenotypes (eg, insulin …

Ovarian reserve (OR) and fertility are critical in women's healthcare. Clinical methods for
encoding OR and fertility rely on the combination of tests, which cannot serve as a multi …

Exosome metabolite-based noninvasive liquid biopsy is an emerging research hotspot that
tends to substitute current means in clinics. Nanostructure-based mass spectrometry …