Hybrid immunity to SARS-CoV-2 from infection and vaccination—evidence synthesis and implications for new COVID-19 vaccines

JR Spinardi, A Srivastava - Biomedicines, 2023 - mdpi.com
COVID-19 has taken a severe toll on the global population through infections,
hospitalizations, and deaths. Elucidating SARS-CoV-2 infection-derived immunity has led to …

New insights into human immune memory from SARS‐CoV‐2 infection and vaccination

GE Hartley, ESJ Edwards, RE O'Hehir, MC van Zelm - Allergy, 2022 - Wiley Online Library
Since early 2020, the world has been embroiled in an ongoing viral pandemic with SARS‐
CoV‐2 and emerging variants resulting in mass morbidity and an estimated 6 million deaths …

Antigenic sin of wild-type SARS-CoV-2 vaccine shapes poor cross-neutralization of BA. 4/5/2.75 subvariants in BA. 2 breakthrough infections

B Ju, Q Fan, M Wang, X Liao, H Guo, H Wang… - Nature …, 2022 - nature.com
Abstract With declining SARS-CoV-2-specific antibody titers and increasing numbers of
spike mutations, the ongoing emergence of Omicron subvariants causes serious challenges …

Three-dose vaccination-induced immune responses protect against SARS-CoV-2 Omicron BA. 2: a population-based study in Hong Kong

R Zhou, N Liu, X Li, Q Peng, CK Yiu… - The Lancet Regional …, 2023 - thelancet.com
Background The ongoing outbreak of SARS-CoV-2 Omicron BA. 2 infections in Hong Kong,
the model city of universal masking of the world, has resulted in a major public health crisis …

Computational investigation of natural compounds as potential main protease (Mpro) inhibitors for SARS-CoV-2 virus

CN Patel, SP Jani, SP Kumar, KM Modi… - Computers in Biology and …, 2022 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is significantly impacting human lives …

Viable SARS-CoV-2 Omicron sub-variants isolated from autopsy tissues

S Maffia-Bizzozero, C Cevallos, FR Lenicov… - Frontiers in …, 2023 - frontiersin.org
Introduction Pulmonary and extrapulmonary manifestations have been described after
infection with SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Omicron variants breakthrough infection elicited higher specific memory immunity than third dose booster in healthy vaccinees

P Yu, Z Liu, Z Zhu, J Yang, M Deng, M Chen, C Lai… - Virologica Sinica, 2023 - Elsevier
Homologous booster, heterologous booster, and Omicron variants breakthrough infection
(OBI) could improve the humoral immunity against Omicron variants. Questions concerning …

Original antigen sin and COVID-19: implications for seasonal vaccination

MW McCarthy - Expert Opinion on Biological Therapy, 2022 - Taylor & Francis
Introduction Original antigenic sin describes the phenomenon in which immunity against
pathogens or antigens is shaped by the host's first exposure to a related pathogen or …

RSV A2-based prefusion F vaccine candidates induce RSV A and RSV B cross binding and neutralizing antibodies and provide protection against RSV A and RSV B …

F Cox, E Saeland, A Thoma, W van den Hoogen… - Vaccines, 2023 - mdpi.com
RSV is divided into two antigenic subtypes, RSV A and RSV B, which is largely based on the
variation in the G protein, while the fusion protein F is more conserved and a target for …

SARS-CoV-2 BA. 1 and BA. 2 breakthrough infections boost antibody responses to early Omicron subvariants but not BQ. 1.1 or XBB. 1.5

A Abbad, T Yellin, G Singh, M Fried, A Raskin… - Cell Reports …, 2024 - cell.com
Subvariants of the Omicron lineage of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) efficiently escape neutralizing antibody responses induced by both …