Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium

YT Quiroz, M Solis, MP Aranda, AI Arbaje… - Alzheimer's & …, 2022 - Wiley Online Library
Abstract The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium
in May 2021. Due to the COVID‐19 pandemic, the meeting was held online over 2 days, with …

Disparities by race and ethnicity among adults recruited for a preclinical Alzheimer disease trial

R Raman, YT Quiroz, O Langford, J Choi… - JAMA Network …, 2021 - jamanetwork.com
Importance Underrepresentation of many racial/ethnic groups in Alzheimer disease (AD)
clinical trials limits generalizability of results and hinders opportunities to examine potential …

Eligibility rates among racially and ethnically diverse US participants in phase 2 and phase 3 placebo‐controlled, double‐blind, randomized trials of Lecanemab and …

JD Grill, C Flournoy, S Dhadda, K Ernstrom… - Annals of …, 2024 - Wiley Online Library
Objective Many factors contribute to inadequate diversity in Alzheimer disease (AD) clinical
trials. We evaluated eligibility rates among racial and ethnic groups at US sites in large …

A call to address structural barriers to Hispanic/Latino representation in clinical trials on Alzheimer's disease and related dementias: A micro‐meso‐macro perspective

MP Aranda, DX Marquez… - … Research & Clinical …, 2023 - Wiley Online Library
Introduction This perspective paper addresses the US Hispanic/Latino (herein, Latino)
experience with regards to a significant public health concern—the underrepresentation of …

[HTML][HTML] Tackling a major deficiency of diversity in Alzheimer's disease therapeutic trials: an CTAD task force report

R Raman, P Aisen, MC Carillo, M Detke, JD Grill… - The journal of …, 2022 - Springer
As the last opportunity to assess treatment effect modification in a controlled setting prior to
formal approval, clinical trials are a critical tool for understanding the safety and efficacy of …

Synthesizing best practices to promote health equity for older adults through community-engaged research

F Epps, J Gore, JD Flatt, IC Williams… - Research in …, 2024 - journals.healio.com
Achieving health equity requires creating evidence that reflects the nuance and diversity of
experiences among populations disproportionately impacted by age-and race-related …

What should the goals be for diverse recruitment in Alzheimer clinical trials?

JD Grill, RA Sperling, R Raman - JAMA neurology, 2022 - jamanetwork.com
Alzheimer disease (AD) disproportionately affects women and people from racial and ethnic
minority groups and is an active area of therapeutic research to develop interventions that …

Brain health registry updates: An online longitudinal neuroscience platform

MW Weiner, A Aaronson, J Eichenbaum… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Remote, internet‐based methods for recruitment, screening, and longitudinally
assessing older adults have the potential to facilitate Alzheimer's disease (AD) clinical trials …

[HTML][HTML] Communication Bridge™-2 (CB2): an NIH Stage 2 randomized control trial of a speech-language intervention for communication impairments in individuals …

AC Roberts, AW Rademaker, EA Salley, A Mooney… - Trials, 2022 - Springer
Background Primary progressive aphasia (PPA) is a clinical dementia syndrome.
Impairments in language (speaking, reading, writing, and understanding) are the primary …

Stability and change in acculturation‐related characteristics in older Latinos: Implications for culturally compatible ADRD research

M Lamar, CM Glover, AW Capuano… - … Research & Clinical …, 2023 - Wiley Online Library
Introduction Acculturation‐related characteristics, that is, factors directly connected to culture
and familial relationships, are associated with engaged research participation within Latino …