Mitochondria ROS and mitophagy in acute kidney injury
Mitophagy is an essential mitochondrial quality control mechanism that eliminates damaged
mitochondria and the production of reactive oxygen species (ROS). The relationship …
mitochondria and the production of reactive oxygen species (ROS). The relationship …
[HTML][HTML] Programmed cell death in sepsis associated acute kidney injury
Z Wu, J Deng, H Zhou, W Tan, L Lin, J Yang - Frontiers in Medicine, 2022 - frontiersin.org
Sepsis-associated acute kidney injury (SA-AKI) is common in patients with severe sepsis,
and has a high incidence rate and high mortality rate in ICU patients. Most patients progress …
and has a high incidence rate and high mortality rate in ICU patients. Most patients progress …
[HTML][HTML] 4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling
L Xu, J Cai, C Li, M Yang, T Duan, Q Zhao, Y Xi… - Molecular …, 2023 - Springer
Background Septic acute kidney injury (S-AKI) is the leading form of acute kidney failure
among hospitalized patients, and the inflammatory response is involved in this process. 4 …
among hospitalized patients, and the inflammatory response is involved in this process. 4 …
[HTML][HTML] Baicalein Induces Mitochondrial Autophagy to Prevent Parkinson's Disease in Rats via miR-30b and the SIRT1/AMPK/mTOR Pathway
M Chen, L Peng, P Gong, X Zheng, T Sun… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is a prevailing neurodegenerative disorder. Baicalein has
neuroprotective effects on PD animals, but its mechanism is not clarified. We explored …
neuroprotective effects on PD animals, but its mechanism is not clarified. We explored …
[HTML][HTML] Sepsis-Associated Acute Kidney Injury: Where Are We Now?
D Kounatidis, NG Vallianou, S Psallida… - Medicina, 2024 - mdpi.com
Worldwide, sepsis is a well-recognized cause of death. Acute kidney injury (AKI) may be
related to sepsis in up to 70% of AKI cases. Sepsis-associated AKI (SA-AKI) is defined as the …
related to sepsis in up to 70% of AKI cases. Sepsis-associated AKI (SA-AKI) is defined as the …
[HTML][HTML] Fatty acid β-oxidation in kidney diseases: perspectives on pathophysiological mechanisms and therapeutic opportunities
Z Gao, X Chen - Frontiers in Pharmacology, 2022 - frontiersin.org
The kidney is a highly metabolic organ and requires a large amount of ATP to maintain its
filtration-reabsorption function, and mitochondrial fatty acid β-oxidation serves as the main …
filtration-reabsorption function, and mitochondrial fatty acid β-oxidation serves as the main …
[HTML][HTML] Exosomes from adipose-derived stem cells inhibit inflammation and oxidative stress in LPS-acute kidney injury
W Zhang, J Zhang, H Huang - Experimental cell research, 2022 - Elsevier
Acute renal damage presents a significant danger to kidney health. Previous research has
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …
Mesenchymal stem cell therapy in kidney diseases: potential and challenges
F Chen, NN Chen, C Xia, H Wang, L Shao… - Cell …, 2023 - journals.sagepub.com
Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …
mortality in clinical settings, which can be caused by many reasons, and the incidence …
[HTML][HTML] The mitochondrion: A promising target for kidney disease
Mitochondrial dysfunction is important in the pathogenesis of various kidney diseases and
the mitochondria potentially serve as therapeutic targets necessitating further investigation …
the mitochondria potentially serve as therapeutic targets necessitating further investigation …
[HTML][HTML] The dual role of mesenchymal stem cells in apoptosis regulation
Z Chen, X Xia, M Yao, Y Yang, X Ao, Z Zhang… - Cell Death & …, 2024 - nature.com
Mesenchymal stem cells (MSCs) are widely distributed pluripotent stem cells with powerful
immunomodulatory capacity. MSCs transplantation therapy (MSCT) is widely used in the …
immunomodulatory capacity. MSCs transplantation therapy (MSCT) is widely used in the …