Normal cognitive and social development require posterior cerebellar activity

A Badura, JL Verpeut, JW Metzger, TD Pereira… - Elife, 2018 - elifesciences.org
Cognitive and social capacities require postnatal experience, yet the pathways by which
experience guides development are unknown. Here we show that the normal development …

[HTML][HTML] Reinforcement learning in autism spectrum disorder

M Schuetze, CS Rohr, D Dewey, A McCrimmon… - Frontiers in …, 2017 - frontiersin.org
Early behavioral interventions are recognized as integral to standard care in autism
spectrum disorder (ASD), and often focus on reinforcing desired behaviors (eg, eye contact) …

[HTML][HTML] Visualizing the human subcortex using ultra-high field magnetic resonance imaging

MC Keuken, BR Isaacs, R Trampel, W Van Der Zwaag… - Brain topography, 2018 - Springer
With the recent increased availability of ultra-high field (UHF) magnetic resonance imaging
(MRI), substantial progress has been made in visualizing the human brain, which can now …

[HTML][HTML] The cerebellum contributes to context-effects during fear extinction learning: A 7T fMRI study

G Batsikadze, N Diekmann, TM Ernst, M Klein… - Neuroimage, 2022 - Elsevier
The cerebellum is involved in the acquisition and consolidation of learned fear responses.
Knowledge about its contribution to extinction learning, however, is sparse. Extinction …

The cerebellum is involved in processing of predictions and prediction errors in a fear conditioning paradigm

TM Ernst, AE Brol, M Gratz, C Ritter, U Bingel… - elife, 2019 - elifesciences.org
Prediction errors are thought to drive associative fear learning. Surprisingly little is known
about the possible contribution of the cerebellum. To address this question, healthy …

Nighres: processing tools for high-resolution neuroimaging

JM Huntenburg, CJ Steele, PL Bazin - GigaScience, 2018 - academic.oup.com
With recent improvements in human magnetic resonance imaging (MRI) at ultra-high fields,
the amount of data collected per subject in a given MRI experiment has increased …

Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input

HJ Boele, S Peter, MM Ten Brinke, L Verdonschot… - Science …, 2018 - science.org
Pavlovian eyeblink conditioning has been used extensively to study the neural mechanisms
underlying associative and motor learning. During this simple learning task, memory …

Pre-ataxic loss of intrinsic plasticity and motor learning in a mouse model of SCA1

C Osório, JJ White, H Lu, GC Beekhof, FR Fiocchi… - Brain, 2023 - academic.oup.com
Spinocerebellar ataxias are neurodegenerative diseases, the hallmark symptom of which is
the development of ataxia due to cerebellar dysfunction. Purkinje cells, the principal neurons …

Using optically pumped magnetometers to measure magnetoencephalographic signals in the human cerebellum

CH Lin, TM Tierney, N Holmes, E Boto… - The Journal of …, 2019 - Wiley Online Library
Key points The application of conventional cryogenic magnetoencephalography (MEG) to
the study of cerebellar functions is highly limited because typical cryogenic sensor arrays …

[HTML][HTML] Neurocognitive and cerebellar function in ADHD, autism and spinocerebellar ataxia

M Cundari, S Vestberg, P Gustafsson… - Frontiers in Systems …, 2023 - frontiersin.org
The cerebellum plays a major role in s balance, motor control and sensorimotor integration,
but also cognition, language, and emotional regulation. Several neuropsychiatric disorders …