There is an increasing understanding of the molecular and cytogenetic background of
various tumors that helps us better conceptualize the pathogenesis of specific diseases …

Background As we know, chemotherapy resistance is a critical factor leading to recurrence
and metastasis of nonsmall-cell lung cancer (NSCLC). To clarify the key target and potential …

Lung cancer is one of the most common malignant tumours worldwide, with the highest
mortality rate. Approximately 1.6 million deaths owing to lung cancer are reported annually; …

Objective Sepsis is the most common cause of death in the intensive care unit. Moreover,
sepsis is the leading cause of acute lung injury (ALI). Serine-arginine protein kinase 1 …

Simple Summary The main histological subtypes of lung cancer are small-cell lung cancer
(SCLC) and non-small-cell lung cancer (NSCLC). NSCLC is further subdivided into …

Oncogenic mutations in the RAS family of small GTPases are commonly found in human
cancers and they promote tumorigenesis by altering gene expression networks. We …

Uterine glands and their secretions are crucial for conceptus survival and implantation in
rodents and humans. In mice, the development of uterine gland known as adenogenesis …

ABSTRACT PTEN/AKT signaling cascade is frequently activated in various cancers,
including lung cancer. The downstream effector of this signaling cascade is poorly …

Aging is an inevitable risk factor for many diseases, including cardiovascular diseases,
neurodegenerative diseases, cancer, and diabetes. Investigation into the molecular …

Recent studies have noted the role of the phosphatase and tensin homolog deleted on
chromosome 10 (PTEN) in developing neuropathic pain, but the underlying mechanisms are …