[HTML][HTML] Defects in nicotinamide-adenine dinucleotide phosphate oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease
P Hayes, S Dhillon, K O'Neill, C Thoeni, KY Hui… - Cellular and molecular …, 2015 - Elsevier
Background & Aims Defects in intestinal innate defense systems predispose patients to
inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by …
inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by …
Incidence and phenotype at diagnosis of very-early-onset compared with later-onset paediatric inflammatory bowel disease: a population-based study [1988–2011]
E Bequet, H Sarter, M Fumery, F Vasseur… - Journal of Crohn's …, 2017 - academic.oup.com
Abstract Background and Aims: Very-early-onset inflammatory bowel disease [VEO-IBD] is a
form of IBD that is distinct from that of children with an older onset. We compared changes …
form of IBD that is distinct from that of children with an older onset. We compared changes …
Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease
Background & Aims Very early onset inflammatory bowel disease (VEO-IBD), IBD diagnosed
at 5 years of age or younger, frequently presents with a different and more severe phenotype …
at 5 years of age or younger, frequently presents with a different and more severe phenotype …
[HTML][HTML] Influence of environmental factors in the development of inflammatory bowel diseases
Idiopathic inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis
(UC), are multifactorial diseases that are manifested after disruption of a genetic …
(UC), are multifactorial diseases that are manifested after disruption of a genetic …
Mechanisms of pediatric inflammatory bowel disease
Inflammatory bowel disease (IBD), including Crohn disease and ulcerative colitis, is
characterized by chronic intestinal inflammation due to a complex interaction of genetic …
characterized by chronic intestinal inflammation due to a complex interaction of genetic …
The impact of inflammatory bowel disease in Canada 2018: A scientific report from the Canadian Gastro-Intestinal Epidemiology Consortium to Crohn's and Colitis …
EI Benchimol, CN Bernstein, A Bitton… - Journal of the …, 2019 - academic.oup.com
Canada has among the highest rates of IBD in the world, and the number of people living
with these disorders is growing rapidly. This has placed a high burden on the health care …
with these disorders is growing rapidly. This has placed a high burden on the health care …
[PDF][PDF] Recent advance in very early onset inflammatory bowel disease
JO Shim - Pediatric gastroenterology, hepatology & nutrition, 2019 - synapse.koreamed.org
Recent studies on pediatric inflammatory bowel disease (IBD) have revealed that early-
onset IBD has distinct phenotypic differences compared with adult-onset IBD. In particular …
onset IBD has distinct phenotypic differences compared with adult-onset IBD. In particular …
Clinical phenotypes and outcomes in monogenic versus non-monogenic very early onset inflammatory bowel disease
LV Collen, DY Kim, M Field, I Okoroafor… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Over 80 monogenic causes of very early onset inflammatory
bowel disease [VEOIBD] have been identified. Prior reports of the natural history of VEOIBD …
bowel disease [VEOIBD] have been identified. Prior reports of the natural history of VEOIBD …
Intercellular adhesion molecule-1 enhances the therapeutic effects of MSCs in a dextran sulfate sodium-induced colitis models by promoting MSCs homing to murine …
X Li, Q Wang, L Ding, YX Wang, ZD Zhao… - Stem Cell Research & …, 2019 - Springer
Background To investigate the therapeutic effect of intercellular adhesion molecule (ICAM)-1-
modified mesenchymal stem cells (MSCs) in a mouse model of inflammatory bowel disease …
modified mesenchymal stem cells (MSCs) in a mouse model of inflammatory bowel disease …
Clinical presentation and five-year therapeutic management of very early-onset inflammatory bowel disease in a large North American cohort
M Oliva-Hemker, S Hutfless, ES Al Kazzi, T Lerer… - The Journal of …, 2015 - Elsevier
Objective To evaluate the presentation, therapeutic management, and long-term outcome of
children with very early-onset (VEO)(≤ 5 years of age) inflammatory bowel disease (IBD) …
children with very early-onset (VEO)(≤ 5 years of age) inflammatory bowel disease (IBD) …