[HTML][HTML] Integrative toxicogenomics: Advancing precision medicine and toxicology through artificial intelligence and OMICs technology
More information about a person's genetic makeup, drug response, multi-omics response,
and genomic response is now available leading to a gradual shift towards personalized …
and genomic response is now available leading to a gradual shift towards personalized …
Addressing ancestry and sex bias in pharmacogenomics
M Corpas, MK Siddiqui, O Soremekun… - Annual review of …, 2024 - annualreviews.org
The association of an individual's genetic makeup with their response to drugs is referred to
as pharmacogenomics. By understanding the relationship between genetic variants and …
as pharmacogenomics. By understanding the relationship between genetic variants and …
[PDF][PDF] Evolutionary genetics and admixture in African populations
A Pfennig, LN Petersen, P Kachambwa… - Genome Biology and …, 2023 - academic.oup.com
As the ancestral homeland of our species, Africa contains elevated levels of genetic diversity
and substantial population structure. Importantly, African genomes are heterogeneous: They …
and substantial population structure. Importantly, African genomes are heterogeneous: They …
Warfarin pharmacogenomics for precision medicine in real-life clinical practice in southern Africa: Harnessing 73 variants in 29 pharmacogenes
Pharmacogenomics is universally relevant for worldwide modern therapeutics and yet
needs further development in resource-limited countries. While there is an abundance of …
needs further development in resource-limited countries. While there is an abundance of …
Major genetic drivers of statin treatment response in African populations and pharmacogenetics of dyslipidemia through a One Health lens
A One Health lens is increasingly significant to address the intertwined challenges in
planetary health concerned with the health of humans, nonhuman animals, plants, and …
planetary health concerned with the health of humans, nonhuman animals, plants, and …
Towards evidence-based implementation of pharmacogenomics in southern Africa: comorbidities and polypharmacy profiles across diseases
ND Soko, S Muyambo, MTL Dandara… - Journal of Personalized …, 2023 - mdpi.com
Pharmacogenomics may improve patient care by guiding drug selection and dosing;
however, this requires prior knowledge of the pharmacogenomics of drugs commonly used …
however, this requires prior knowledge of the pharmacogenomics of drugs commonly used …
Pharmacogenomics of Hypertension in Africa: Paving the Way for a Pharmacogenetic‐Based Approach for the Treatment of Hypertension in Africans
JN Katsukunya, ND Soko, J Naidoo… - International Journal …, 2023 - Wiley Online Library
In Africa, the burden of hypertension has been rising at an alarming rate for the last two
decades and is a major cause for cardiovascular disease (CVD) mortality and morbidity …
decades and is a major cause for cardiovascular disease (CVD) mortality and morbidity …
Genomic medicine in Africa: a need for molecular genetics and pharmacogenomics experts
OG Oluwole, M Henry - Current Medical Research and Opinion, 2023 - Taylor & Francis
The large-scale implementation of genomic medicine in Africa has not been actualized. This
overview describes how routine molecular genetics and advanced protein …
overview describes how routine molecular genetics and advanced protein …
Warfarin pharmacogenomics in African populations: the importance of ethnicity-based algorithms
M Jallul, I Alhudiri, L Al-Eitan, A Elzagheid - Pharmacogenomics, 2022 - Taylor & Francis
Full article: Warfarin Pharmacogenomics in African Populations: The Importance of Ethnicity-Based
Algorithms Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …
Algorithms Skip to Main Content Taylor and Francis Online homepage Taylor and Francis …
The Case for Pre-Emptive Pharmacogenetic Screening in South Africa
T Hurrell, J Naidoo, C Masimirembwa… - Journal of Personalized …, 2024 - mdpi.com
Lack of equitable representation of global genetic diversity has hampered the
implementation of genomic medicine in under-represented populations, including those on …
implementation of genomic medicine in under-represented populations, including those on …