Exposure to per-and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis

E Costello, S Rock, N Stratakis, SP Eckel… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Experimental evidence indicates that exposure to certain pollutants is
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …

Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

[HTML][HTML] Exposure to environmental contaminants is associated with altered hepatic lipid metabolism in non-alcoholic fatty liver disease

P Sen, S Qadri, PK Luukkonen, O Ragnarsdottir… - Journal of …, 2022 - Elsevier
Background & aims Recent experimental models and epidemiological studies suggest that
specific environmental contaminants (ECs) contribute to the initiation and pathology of non …

Obesity II: establishing causal links between chemical exposures and obesity

JJ Heindel, S Howard, K Agay-Shay, JP Arrebola… - Biochemical …, 2022 - Elsevier
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …

[HTML][HTML] Intestinal barrier and permeability in health, obesity and NAFLD

P Portincasa, L Bonfrate, M Khalil, MD Angelis… - Biomedicines, 2021 - mdpi.com
The largest surface of the human body exposed to the external environment is the gut. At this
level, the intestinal barrier includes luminal microbes, the mucin layer, gastrointestinal …

[HTML][HTML] Sources, characteristics, toxicity, and control of ultrafine particles: An overview

AL Moreno-Ríos, LP Tejeda-Benítez… - Geoscience …, 2022 - Elsevier
Air pollution by particulate matter (PM) is one of the main threats to human health,
particularly in large cities where pollution levels are continually exceeded. According to their …

[HTML][HTML] Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort

JA Goodrich, D Walker, X Lin, H Wang, T Lim… - JHEP Reports, 2022 - Elsevier
Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …

[HTML][HTML] Liver steatosis, gut-liver axis, microbiome and environmental factors. A never-ending bidirectional cross-talk

A Di Ciaula, J Baj, G Garruti, G Celano… - Journal of clinical …, 2020 - mdpi.com
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing worldwide and
parallels comorbidities such as obesity, metabolic syndrome, dyslipidemia, and diabetes …

[HTML][HTML] Oxidative stress in NAFLD: role of nutrients and food contaminants

C Rives, A Fougerat, S Ellero-Simatos, N Loiseau… - Biomolecules, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Prenatal exposure to perfluoroalkyl substances associated with increased susceptibility to liver injury in children

N Stratakis, DV Conti, R Jin, K Margetaki, D Valvi… - Hepatology, 2020 - journals.lww.com
The severe acute respiratory syndrome coronavirus 2 pandemic has drastically altered all
facets of clinical care and research. Clinical research in hepatology has had a rich tradition …