Recently, circular RNAs (circRNAs) have appealed to a growing interest due to their
abundant expression and potential functions in cancer development. The most biological …

RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …

Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …

Esophageal squamous cell carcinoma (ESCC) is one of the most common human
malignancies worldwide and is associated with high morbidity and mortality. More than 70 …

Esophageal squamous cell carcinoma (ESCC) is one of the most life-and health-threatening
malignant diseases worldwide, especially in China. Long noncoding RNAs (lncRNAs) have …

Cancer is driven by both germline and somatic genetic changes. Efforts have been devoted
to characterizing essential genetic variations in cancer initiation and development. Most …

Aberrant DNA methylation is one of the earliest hallmarks of cancer. DNMT1 is responsible
for methylating newly replicated DNA, but the precise regulation of DNMT1 to ensure faithful …

Exosomal long non-coding RNAs (lncRNAs) have emerged as a cell-free biomarker for
clinical evaluation of cancers. However, the potential clinical applications of exosomal …

Long noncoding RNAs (lncRNAs) play fundamental roles in cancer development; however,
the underlying mechanisms for a large proportion of lncRNAs in pancreatic ductal …

Background Thyroid carcinoma (THCA) is the most common endocrine-related malignant
tumor. Despite the good prognosis, some THCA patients may deteriorate into more …