[HTML][HTML] The new scope of virus taxonomy: partitioning the virosphere into 15 hierarchical ranks

Nature Microbiology, 2020 - nature.com
Virus taxonomy emerged as a discipline in the middle of the twentieth century. Traditionally,
classification by virus taxonomists has been focussed on the grouping of relatively closely …

[HTML][HTML] Horizontal gene transfer of antibiotic resistance genes in biofilms

C Michaelis, E Grohmann - Antibiotics, 2023 - mdpi.com
Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix
which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it …

Diverse enzymatic activities mediate antiviral immunity in prokaryotes

L Gao, H Altae-Tran, F Böhning, KS Makarova, M Segel… - Science, 2020 - science.org
Bacteria and archaea are frequently attacked by viruses and other mobile genetic elements
and rely on dedicated antiviral defense systems, such as restriction endonucleases and …

Molecular and evolutionary determinants of bacteriophage host range

PA de Jonge, FL Nobrega, SJJ Brouns, BE Dutilh - Trends in microbiology, 2019 - cell.com
The host range of a bacteriophage is the taxonomic diversity of hosts it can successfully
infect. Host range, one of the central traits to understand in phages, is determined by a range …

[HTML][HTML] Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection

E Maffei, A Shaidullina, M Burkolter, Y Heyer… - PLoS …, 2021 - journals.plos.org
Bacteriophages, the viruses infecting bacteria, hold great potential for the treatment of
multidrug-resistant bacterial infections and other applications due to their unparalleled …

Revisiting the rules of life for viruses of microorganisms

AMS Correa, C Howard-Varona, SR Coy… - Nature Reviews …, 2021 - nature.com
Viruses that infect microbial hosts have traditionally been studied in laboratory settings with
a focus on either obligate lysis or persistent lysogeny. In the environment, these infection …

[HTML][HTML] Thousands of previously unknown phages discovered in whole-community human gut metagenomes

S Benler, N Yutin, D Antipov, M Rayko, S Shmakov… - Microbiome, 2021 - Springer
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …

Origin of viruses: primordial replicators recruiting capsids from hosts

M Krupovic, VV Dolja, EV Koonin - Nature Reviews Microbiology, 2019 - nature.com
Viruses are ubiquitous parasites of cellular life and the most abundant biological entities on
Earth. It is widely accepted that viruses are polyphyletic, but a consensus scenario for their …

Viruses defined by the position of the virosphere within the replicator space

EV Koonin, VV Dolja, M Krupovic… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …