Thyroid dysfunction (TD) is common in metabolic disorders such as diabetes mellitus (DM),
cardiovascular disease (CVD), obesity, dyslipidemia, hyperuricemia, kidney and liver …

Thyroxine and triiodothyronine (T3) are classical thyroid hormones and with relatively well-
understood actions. In contrast, the physiological role of thyroid hormone metabolites, also …

Background Cardiac re-expression of fetal genes in patients with heart failure (HF) suggests
the presence of low cardiac tissue thyroid hormone (TH) function. However, serum …

Background Advanced type 2 diabetes mellitus (T2DM) accelerates vascular smooth muscle
cell (VSMC) dysfunction which contributes to the development of vasculopathy, associated …

Abnormal thyroid hormone (TH) function has been observed in all components of metabolic
syndrome (MetS), but the mechanisms remain unclear. Altered genomic methylation status …

Interventions: Immediate interventions comprised diuretic administration, oxygen therapy,
and antiarrhythmic agents, addressing acute heart failure concomitant with preexcitation …

Background: Vascular dysfunction constitutes the etiology of many diseases, such as
myocardial infarction and hypertension, with the disruption of redox homeostasis playing a …

Fundamento A disfunção vascular constitui a etiologia de diversas doenças, incluindo
infarto do miocárdio e hipertensão, diante da ruptura da homeostase oxi-redutiva (“redox”) …

Background High salt-diets have become significant threats to human health, resulting in
hypertension and cardiovascular diseases. Hypertensive disorders during pregnancy are …

Subarachnoid hemorrhage (SAH) due to rupture of an intracranial aneurysm leads to
vasospasm resulting in delayed cerebral ischemia. Therapeutic options are currently limited …